2pc6: Difference between revisions
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[[Image:2pc6.gif|left|200px]] | [[Image:2pc6.gif|left|200px]] | ||
'''Crystal structure of putative acetolactate synthase- small subunit from Nitrosomonas europaea''' | {{Structure | ||
|PDB= 2pc6 |SIZE=350|CAPTION= <scene name='initialview01'>2pc6</scene>, resolution 2.50Å | |||
|SITE= | |||
|LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene> and <scene name='pdbligand=SIN:SUCCINIC ACID'>SIN</scene> | |||
|ACTIVITY= [http://en.wikipedia.org/wiki/Acetolactate_synthase Acetolactate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.2.1.6 2.2.1.6] | |||
|GENE= ilvH, NE1324 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=228410 Nitrosomonas europaea ATCC 19718]) | |||
}} | |||
'''Crystal structure of putative acetolactate synthase- small subunit from Nitrosomonas europaea''' | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
2PC6 is a [ | 2PC6 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Nitrosomonas_europaea_atcc_19718 Nitrosomonas europaea atcc 19718]. This structure supersedes the now removed PDB entry 2FGD. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PC6 OCA]. | ||
==Reference== | ==Reference== | ||
Crystal structures of TM0549 and NE1324--two orthologs of E. coli AHAS isozyme III small regulatory subunit., Petkowski JJ, Chruszcz M, Zimmerman MD, Zheng H, Skarina T, Onopriyenko O, Cymborowski MT, Koclega KD, Savchenko A, Edwards A, Minor W, Protein Sci. 2007 Jul;16(7):1360-7. PMID:[http:// | Crystal structures of TM0549 and NE1324--two orthologs of E. coli AHAS isozyme III small regulatory subunit., Petkowski JJ, Chruszcz M, Zimmerman MD, Zheng H, Skarina T, Onopriyenko O, Cymborowski MT, Koclega KD, Savchenko A, Edwards A, Minor W, Protein Sci. 2007 Jul;16(7):1360-7. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17586771 17586771] | ||
[[Category: Acetolactate synthase]] | [[Category: Acetolactate synthase]] | ||
[[Category: Nitrosomonas europaea atcc 19718]] | [[Category: Nitrosomonas europaea atcc 19718]] | ||
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[[Category: lyase]] | [[Category: lyase]] | ||
[[Category: mcsg]] | [[Category: mcsg]] | ||
[[Category: midwest center for structural | [[Category: midwest center for structural genomic]] | ||
[[Category: protein structure initiative]] | [[Category: protein structure initiative]] | ||
[[Category: psi]] | [[Category: psi]] | ||
[[Category: regulatory subunit]] | [[Category: regulatory subunit]] | ||
[[Category: structural | [[Category: structural genomic]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:11:25 2008'' | ||
Revision as of 19:11, 20 March 2008
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| , resolution 2.50Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | and | ||||||
| Gene: | ilvH, NE1324 (Nitrosomonas europaea ATCC 19718) | ||||||
| Activity: | Acetolactate synthase, with EC number 2.2.1.6 | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Crystal structure of putative acetolactate synthase- small subunit from Nitrosomonas europaea
OverviewOverview
Crystal structures of two orthologs of the regulatory subunit of acetohydroxyacid synthase III (AHAS, EC 2.2.1.6) from Thermotoga maritima (TM0549) and Nitrosomonas europea (NE1324) were determined by single-wavelength anomalous diffraction methods with the use of selenomethionine derivatives at 2.3 A and 2.5 A, respectively. TM0549 and NE1324 share the same fold, and in both proteins the polypeptide chain contains two separate domains of a similar size. Each protein contains a C-terminal domain with ferredoxin-type fold and an N-terminal ACT domain, of which the latter is characteristic for several proteins involved in amino acid metabolism. The ferredoxin domain is stabilized by a calcium ion in the crystal structure of NE1324 and by a Mg(H2O)(6)2+ ion in TM0549. Both TM0549 and NE1324 form dimeric assemblies in the crystal lattice.
About this StructureAbout this Structure
2PC6 is a Single protein structure of sequence from Nitrosomonas europaea atcc 19718. This structure supersedes the now removed PDB entry 2FGD. Full crystallographic information is available from OCA.
ReferenceReference
Crystal structures of TM0549 and NE1324--two orthologs of E. coli AHAS isozyme III small regulatory subunit., Petkowski JJ, Chruszcz M, Zimmerman MD, Zheng H, Skarina T, Onopriyenko O, Cymborowski MT, Koclega KD, Savchenko A, Edwards A, Minor W, Protein Sci. 2007 Jul;16(7):1360-7. PMID:17586771
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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)
OCA- Pages with broken file links
- Acetolactate synthase
- Nitrosomonas europaea atcc 19718
- Single protein
- Chruszcz, M.
- Cymborowski, M T.
- Edwards, A.
- Joachimiak, A.
- MCSG, Midwest Center for Structural Genomics.
- Minor, W.
- Onopriyenko, O.
- Petkowski, J J.
- Savchenko, A.
- Skarina, T.
- Zheng, H.
- Zimmerman, M D.
- CA
- SIN
- Lyase
- Mcsg
- Midwest center for structural genomic
- Protein structure initiative
- Psi
- Regulatory subunit
- Structural genomic