4l6h: Difference between revisions
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{{STRUCTURE_4l6h| PDB=4l6h | SCENE= }} | |||
===Crystal structure of the Candida albicans Methionine Synthase in complex with Methotrexate and Homocysteine=== | |||
{{ABSTRACT_PUBMED_24524835}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/METE_CANAL METE_CANAL]] Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.[HAMAP-Rule:MF_00172] | |||
==About this Structure== | |||
[[4l6h]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L6H OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:024524835</ref><references group="xtra"/><references/> | |||
[[Category: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase]] | |||
[[Category: Robertus, J D.]] | |||
[[Category: Ubhi, D.]] | |||
[[Category: Cobalamin-independent]] | |||
[[Category: Dual tim barrel]] | |||
[[Category: Fungal]] | |||
[[Category: Methionine synthase]] | |||
[[Category: Surface entropy reduction]] | |||
[[Category: Transferase]] | |||
Revision as of 07:24, 9 April 2014
Crystal structure of the Candida albicans Methionine Synthase in complex with Methotrexate and HomocysteineCrystal structure of the Candida albicans Methionine Synthase in complex with Methotrexate and Homocysteine
Template:ABSTRACT PUBMED 24524835
FunctionFunction
[METE_CANAL] Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.[HAMAP-Rule:MF_00172]
About this StructureAbout this Structure
4l6h is a 1 chain structure. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Ubhi D, Kago G, Monzingo AF, Robertus JD. Structural analysis of a fungal methionine synthase with substrates and inhibitors. J Mol Biol. 2014 Apr 17;426(8):1839-47. doi: 10.1016/j.jmb.2014.02.006. Epub 2014, Feb 11. PMID:24524835 doi:http://dx.doi.org/10.1016/j.jmb.2014.02.006