4cc2: Difference between revisions
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{{STRUCTURE_4cc2| PDB=4cc2 | SCENE= }} | |||
===Complex of human Tuba C-terminal SH3 domain with human N-WASP proline- rich peptide - P212121=== | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/DNMBP_HUMAN DNMBP_HUMAN]] Scaffold protein that links dynamin with actin-regulating proteins. May play a role in membrane trafficking between the cell surface and the Golgi (By similarity). [[http://www.uniprot.org/uniprot/WASL_HUMAN WASL_HUMAN]] Regulates actin polymerization by stimulating the actin-nucleating activity of the Arp2/3 complex. Binds to HSF1/HSTF1 and forms a complex on heat shock promoter elements (HSE) that negatively regulates HSP90 expression.<ref>PMID:19366662</ref> | |||
==About this Structure== | |||
[[4cc2]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CC2 OCA]. | |||
==Reference== | |||
<references group="xtra"/><references/> | |||
[[Category: Homo sapiens]] | |||
[[Category: Ireton, K.]] | |||
[[Category: Julian, R.]] | |||
[[Category: Polle, L.]] | |||
[[Category: Rigano, L.]] | |||
[[Category: Schubert, W D.]] | |||
[[Category: Actin cytoskeleton]] | |||
[[Category: Cortical tension]] | |||
[[Category: Proline-rich peptide]] | |||
[[Category: Sh3 domain]] | |||
[[Category: Src homology 3]] | |||
[[Category: Structural protein]] |