2oaz: Difference between revisions

← Older edit Newer edit →

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
-[[Image:2oaz.gif|left|200px]]<br /><applet load="2oaz" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:2oaz.gif|left|200px]]
-caption="2oaz, resolution 1.90&Aring;" />
-'''Human Methionine Aminopeptidase-2 Complexed with SB-587094'''<br />
+ {{Structure
+|PDB= 2oaz |SIZE=350|CAPTION= <scene name='initialview01'>2oaz</scene>, resolution 1.90&Aring;
+|SITE=
+|LIGAND= <scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene> and <scene name='pdbligand=I96:N-(2-ISOPROPYLPHENYL)-3-[(2-THIENYLMETHYL)THIO]-1H-1,2,4-TRIAZOL-5-AMINE'>I96</scene>
+|ACTIVITY= [http://en.wikipedia.org/wiki/Methionyl_aminopeptidase Methionyl aminopeptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.11.18 3.4.11.18]
+|GENE=
+}}
+'''Human Methionine Aminopeptidase-2 Complexed with SB-587094'''
 ==Overview==
@@ Line 7: / Line 16: @@
 ==About this Structure==
-OAZ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=CO:'>CO</scene> and <scene name='pdbligand=I96:'>I96</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Methionyl_aminopeptidase Methionyl aminopeptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.11.18 3.4.11.18] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OAZ OCA].
+OAZ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OAZ OCA].
 ==Reference==
-Highly potent inhibitors of methionine aminopeptidase-2 based on a 1,2,4-triazole pharmacophore., Marino JP Jr, Fisher PW, Hofmann GA, Kirkpatrick RB, Janson CA, Johnson RK, Ma C, Mattern M, Meek TD, Ryan MD, Schulz C, Smith WW, Tew DG, Tomazek TA Jr, Veber DF, Xiong WC, Yamamoto Y, Yamashita K, Yang G, Thompson SK, J Med Chem. 2007 Aug 9;50(16):3777-85. Epub 2007 Jul 18. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17636946 17636946]
+Highly potent inhibitors of methionine aminopeptidase-2 based on a 1,2,4-triazole pharmacophore., Marino JP Jr, Fisher PW, Hofmann GA, Kirkpatrick RB, Janson CA, Johnson RK, Ma C, Mattern M, Meek TD, Ryan MD, Schulz C, Smith WW, Tew DG, Tomazek TA Jr, Veber DF, Xiong WC, Yamamoto Y, Yamashita K, Yang G, Thompson SK, J Med Chem. 2007 Aug 9;50(16):3777-85. Epub 2007 Jul 18. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17636946 17636946]
 [[Category: Homo sapiens]]
 [[Category: Methionyl aminopeptidase]]
@@ Line 41: / Line 50: @@
 [[Category: methionine]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:16:29 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:57:20 2008''