4ag3: Difference between revisions
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==About this Structure== | ==About this Structure== | ||
[[4ag3]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/ | [[4ag3]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseae Pseae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AG3 OCA]. | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:024015914</ref><references group="xtra"/><references/> | <ref group="xtra">PMID:024015914</ref><references group="xtra"/><references/> | ||
[[Category: | [[Category: Pseae]] | ||
[[Category: Cukier, C D.]] | [[Category: Cukier, C D.]] | ||
[[Category: Lindqvist, Y.]] | [[Category: Lindqvist, Y.]] | ||
Revision as of 11:31, 27 November 2013
Crystal structure of 3-ketoacyl-(acyl-carrier-protein) reductase (FabG) from Pseudomonas aeruginosa in complex with NADPH at 1.8A resolutionCrystal structure of 3-ketoacyl-(acyl-carrier-protein) reductase (FabG) from Pseudomonas aeruginosa in complex with NADPH at 1.8A resolution
Template:ABSTRACT PUBMED 24015914
FunctionFunction
[FABG_PSEAE] Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis (By similarity).
About this StructureAbout this Structure
4ag3 is a 4 chain structure with sequence from Pseae. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Cukier CD, Hope AG, Elamin AA, Moynie L, Schnell R, Schach S, Kneuper H, Singh M, Naismith JH, Lindqvist Y, Gray DW, Schneider G. Discovery of an allosteric inhibitor binding site in 3-oxo-acyl-ACP reductase from Pseudomonas aeruginosa. ACS Chem Biol. 2013 Sep 9. PMID:24015914 doi:10.1021/cb4005063