2nyr: Difference between revisions

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[[Image:2nyr.gif|left|200px]]<br /><applet load="2nyr" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2nyr.gif|left|200px]]
caption="2nyr, resolution 2.06&Aring;" />
 
'''Crystal Structure of Human Sirtuin Homolog 5 in Complex with Suramin'''<br />
{{Structure
|PDB= 2nyr |SIZE=350|CAPTION= <scene name='initialview01'>2nyr</scene>, resolution 2.06&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=SVR:8,8'-[CARBONYLBIS[IMINO-3,1-PHENYLENECARBONYLIMINO(4-METHYL-3,1-PHENYLENE)CARBONYLIMINO]]BIS-1,3,5-NAPHTHALENETRISULFONIC+ACID'>SVR</scene> and <scene name='pdbligand=ZN:ZINC ION'>ZN</scene>
|ACTIVITY=
|GENE= SIRT5, SIR2L5 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Crystal Structure of Human Sirtuin Homolog 5 in Complex with Suramin'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2NYR is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=SVR:'>SVR</scene> and <scene name='pdbligand=ZN:'>ZN</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. This structure supersedes the now removed PDB entry 2FZQ. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NYR OCA].  
2NYR is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry 2FZQ. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NYR OCA].  


==Reference==
==Reference==
Structural basis of inhibition of the human NAD+-dependent deacetylase SIRT5 by suramin., Schuetz A, Min J, Antoshenko T, Wang CL, Allali-Hassani A, Dong A, Loppnau P, Vedadi M, Bochkarev A, Sternglanz R, Plotnikov AN, Structure. 2007 Mar;15(3):377-89. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17355872 17355872]
Structural basis of inhibition of the human NAD+-dependent deacetylase SIRT5 by suramin., Schuetz A, Min J, Antoshenko T, Wang CL, Allali-Hassani A, Dong A, Loppnau P, Vedadi M, Bochkarev A, Sternglanz R, Plotnikov AN, Structure. 2007 Mar;15(3):377-89. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17355872 17355872]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: hydrolase]]
[[Category: hydrolase]]
[[Category: sgc]]
[[Category: sgc]]
[[Category: structural genomics]]
[[Category: structural genomic]]
[[Category: structural genomics consortium]]
[[Category: structural genomics consortium]]


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