2ntl: Difference between revisions

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[[Image:2ntl.gif|left|200px]]<br /><applet load="2ntl" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2ntl.gif|left|200px]]
caption="2ntl, resolution 2.60&Aring;" />
 
'''Crystal structure of PurO/AICAR from Methanothermobacter thermoautotrophicus'''<br />
{{Structure
|PDB= 2ntl |SIZE=350|CAPTION= <scene name='initialview01'>2ntl</scene>, resolution 2.60&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=AMZ:AMINOIMIDAZOLE 4-CARBOXAMIDE RIBONUCLEOTIDE'>AMZ</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/IMP_cyclohydrolase IMP cyclohydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.4.10 3.5.4.10]
|GENE= PurO ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=145262 Methanothermobacter thermautotrophicus])
}}
 
'''Crystal structure of PurO/AICAR from Methanothermobacter thermoautotrophicus'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2NTL is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Methanothermobacter_thermautotrophicus Methanothermobacter thermautotrophicus] with <scene name='pdbligand=AMZ:'>AMZ</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/IMP_cyclohydrolase IMP cyclohydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.4.10 3.5.4.10] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NTL OCA].  
2NTL is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Methanothermobacter_thermautotrophicus Methanothermobacter thermautotrophicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NTL OCA].  


==Reference==
==Reference==
A novel function for the N-terminal nucleophile hydrolase fold demonstrated by the structure of an archaeal inosine monophosphate cyclohydrolase., Kang YN, Tran A, White RH, Ealick SE, Biochemistry. 2007 May 1;46(17):5050-62. Epub 2007 Apr 4. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17407260 17407260]
A novel function for the N-terminal nucleophile hydrolase fold demonstrated by the structure of an archaeal inosine monophosphate cyclohydrolase., Kang YN, Tran A, White RH, Ealick SE, Biochemistry. 2007 May 1;46(17):5050-62. Epub 2007 Apr 4. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17407260 17407260]
[[Category: IMP cyclohydrolase]]
[[Category: IMP cyclohydrolase]]
[[Category: Methanothermobacter thermautotrophicus]]
[[Category: Methanothermobacter thermautotrophicus]]
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[[Category: alpha-beta-beta-alpha ntn hydrolase fold]]
[[Category: alpha-beta-beta-alpha ntn hydrolase fold]]


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