3wha: Difference between revisions

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

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-'''Unreleased structure'''
+{{STRUCTURE_3wha|  PDB=3wha  |  SCENE=  }}
+===Hsp90 alpha N-terminal domain in complex with a tricyclic inhibitor===
+{{ABSTRACT_PUBMED_24369839}}
-The entry 3wha is ON HOLD  until Paper Publication
+==Function==
+[[http://www.uniprot.org/uniprot/HS90A_HUMAN HS90A_HUMAN]] Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.<ref>PMID:15937123</ref> <ref>PMID:11274138</ref>
-Authors: Fukami, T.A., Ono, N.
+==About this Structure==
+[[3wha]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WHA OCA].
-Description: Hsp90 alpha N-terminal domain in complex with a tricyclic inhibitor
+==Reference==
+<ref group="xtra">PMID:024369839</ref><references group="xtra"/><references/>
+[[Category: Fukami, T A.]]
+[[Category: Ono, N.]]
+[[Category: Chaperone]]
+[[Category: Chaperone-chaperone inhibitor complex]]