4m49: Difference between revisions
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{{STRUCTURE_4m49| PDB=4m49 | SCENE= }} | |||
===Lactate Dehydrogenase A in complex with a substituted pyrazine inhibitor compound 18=== | |||
==Disease== | |||
[[http://www.uniprot.org/uniprot/LDHA_HUMAN LDHA_HUMAN]] Defects in LDHA are the cause of glycogen storage disease type 11 (GSD11) [MIM:[http://omim.org/entry/612933 612933]]. A metabolic disorder that results in exertional myoglobinuria, pain, cramps and easy fatigue.<ref>PMID:2334430</ref> | |||
==About this Structure== | |||
[[4m49]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M49 OCA]. | |||
==Reference== | |||
<references group="xtra"/><references/> | |||
[[Category: Homo sapiens]] | |||
[[Category: L-lactate dehydrogenase]] | |||
[[Category: Eigenbrot, C.]] | |||
[[Category: Ultsch, M.]] | |||
[[Category: Dehydrogenase/reductase]] | |||
[[Category: Nicotinamide adenine dinucleotide nadh]] | |||
[[Category: Oxidoreductase-oxidoreductase inhibitor complex]] |