4eig: Difference between revisions
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==See Also== | ==See Also== | ||
*[[Antibody|Antibody]] | |||
*[[Dihydrofolate reductase|Dihydrofolate reductase]] | *[[Dihydrofolate reductase|Dihydrofolate reductase]] | ||
Revision as of 12:03, 4 September 2013
CA1698 camel antibody fragment in complex with DHFRCA1698 camel antibody fragment in complex with DHFR
Template:ABSTRACT PUBMED 23911607
FunctionFunction
[DYR_ECOLI] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
About this StructureAbout this Structure
4eig is a 2 chain structure with sequence from Escherichia coli k-12 and Lama glama. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Oyen D, Wechselberger R, Srinivasan V, Steyaert J, Barlow JN. Mechanistic analysis of allosteric and non-allosteric effects arising from nanobody binding to two epitopes of the dihyrofolate reductase of Escherichia coli. Biochim Biophys Acta. 2013 Jul 31. pii: S1570-9639(13)00282-3. doi:, 10.1016/j.bbapap.2013.07.010. PMID:23911607 doi:10.1016/j.bbapap.2013.07.010