4fox: Difference between revisions

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-{{STRUCTURE_4fox|  PDB=4fox  |  SCENE=  }}
+==Crystal Structure of Mtb ThyA in complex with dUMP and Raltitrexed==
-===Crystal Structure of Mtb ThyA in complex with dUMP and Raltitrexed===
+<StructureSection load='4fox' size='340' side='right' caption='[[4fox]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4fox]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_h37rv Mycobacterium tuberculosis h37rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FOX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4FOX FirstGlance]. <br>
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=D16:TOMUDEX'>D16</scene>, <scene name='pdbligand=UMP:2-DEOXYURIDINE+5-MONOPHOSPHATE'>UMP</scene></td></tr>
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3qj7|3qj7]], [[4foa|4foa]], [[4fog|4fog]], [[4fqs|4fqs]]</td></tr>
+<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MT2834, MTV002.29c, Rv2764c, thyA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 Mycobacterium tuberculosis H37Rv])</td></tr>
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thymidylate_synthase Thymidylate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.45 2.1.1.45] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4fox FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fox OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4fox RCSB], [http://www.ebi.ac.uk/pdbsum/4fox PDBsum]</span></td></tr>
+</table>
-==Function==
+==See Also==
-[[http://www.uniprot.org/uniprot/TYSY_MYCTU TYSY_MYCTU]] Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity).
+*[[Thymidylate synthase|Thymidylate synthase]]
+__TOC__
-==About this Structure==
+</StructureSection>
-[[4fox]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_h37rv Mycobacterium tuberculosis h37rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FOX OCA].
 [[Category: Mycobacterium tuberculosis h37rv]]
 [[Category: Thymidylate synthase]]
-[[Category: Bruning, J B.]]
+[[Category: Bruning, J B]]
-[[Category: Harshbarger, W.]]
+[[Category: Harshbarger, W]]
-[[Category: Reddy, M C.M.]]
+[[Category: Reddy, M C.M]]
-[[Category: Sacchettini, J C.]]
+[[Category: Sacchettini, J C]]
-[[Category: TBSGC, TB Structural Genomics Consortium.]]
 [[Category: Structural genomic]]
-[[Category: Tb structural genomics consortium]]
 [[Category: Tbsgc]]
-[[Category: Thymidylate synthase]]
 [[Category: Transferase]]