4lja: Difference between revisions

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-'''Unreleased structure'''
+{{STRUCTURE_4lja|  PDB=4lja  |  SCENE=  }}
+===ClpB NBD2 R621Q from T. thermophilus in complex with AMPPCP and guanidinium chloride===
-The entry 4lja is ON HOLD  until Paper Publication
+==Function==
+[[http://www.uniprot.org/uniprot/CLPB_THET8 CLPB_THET8]] Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.<ref>PMID:10377389</ref>
-Authors: Zeymer, C., Barends, T.R.M., Werbeck, N.D., Schlichting, I., Reinstein, J.
+==About this Structure==
+[[4lja]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LJA OCA].
-Description: ClpB NBD2 R621Q from T. thermophilus in complex with AMPPCP and guanidinium chloride
+==Reference==
+<references group="xtra"/><references/>
+[[Category: Barends, T R.M.]]
+[[Category: Reinstein, J.]]
+[[Category: Schlichting, I.]]
+[[Category: Werbeck, N D.]]
+[[Category: Zeymer, C.]]
+[[Category: Aaa+ protein]]
+[[Category: Chaperone]]
+[[Category: Disaggregase]]
+[[Category: Molecular chaperone]]
+[[Category: Nucleotide binding domain]]