Villin: Difference between revisions
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[[Image:2k6n.png|left|thumb|300px|Crystal Strcture of the | [[Image:2k6n.png|left|thumb|300px|Crystal Strcture of the human supervillin headpiece, [[2k6n]]]] | ||
{{STRUCTURE_2k6n| right| PDB=2k6n | SCENE=Villin/Cv/1 |CAPTION=Human | {{STRUCTURE_2k6n| right| PDB=2k6n | SCENE=Villin/Cv/1 |CAPTION=Human supervillin headpiece, [[2k6n]] }} | ||
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[[Villin]] (VIL) is an actin-binding protein. It contains gelsolin-like domains in its N-terminal and a helical headpiece which binds actin<ref>PMID:10480879</ref>. '''Supervillin (SVIL)''' contains numerous gelsolin-like domains in its C-terminal and interacts with actin. '''Advillin (AVIL)''' is another actin-binding protein in the [[gelsolin]] superfamily which is expressed in the peripheral sensory neurons. '''Cytovillin (CVIL) or ezrin''' serves as intermediate between plasma membrane and actin cytoskeleton. images on the left and right correspond to one representative villin structure, ''i.e.'' the human supervillin headpiece ([[2k6n]]). | [[Villin]] (VIL) is an actin-binding protein. It contains gelsolin-like domains in its N-terminal and a helical headpiece which binds actin<ref>PMID:10480879</ref>. '''Supervillin (SVIL)''' contains numerous gelsolin-like domains in its C-terminal and interacts with actin. '''Advillin (AVIL)''' is another actin-binding protein in the [[gelsolin]] superfamily which is expressed in the peripheral sensory neurons. '''Cytovillin (CVIL) or ezrin or villin-2''' serves as intermediate between plasma membrane and actin cytoskeleton. images on the left and right correspond to one representative villin structure, ''i.e.'' the human supervillin headpiece ([[2k6n]]). | ||
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