4imi: Difference between revisions
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{{STRUCTURE_4imi| PDB=4imi | SCENE= }} | |||
===Novel Modifications on C-terminal Domain of RNA Polymerase II can Fine- tune the Phosphatase Activity of Ssu72.=== | |||
{{ABSTRACT_PUBMED_23844594}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/SYMPK_DROME SYMPK_DROME]] Component of a protein complex required for cotranscriptional processing of 3'-ends of polyadenylated and histone pre-mRNA.<ref>PMID:18042462</ref> <ref>PMID:19450530</ref> | |||
==About this Structure== | |||
[[4imi]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IMI OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:023844594</ref><references group="xtra"/><references/> | |||
[[Category: Drosophila melanogaster]] | |||
[[Category: Phosphoprotein phosphatase]] | |||
[[Category: Luo, Y.]] | |||
[[Category: Yogesha, S D.]] | |||
[[Category: Zhang, Y.]] | |||
[[Category: Ctd]] | |||
[[Category: Ctd phosphatase]] | |||
[[Category: Hydrolase]] | |||
[[Category: Phosphorylated thr4]] | |||
[[Category: Ssu72]] | |||
[[Category: Symplekin]] | |||
Revision as of 23:49, 7 August 2013
Novel Modifications on C-terminal Domain of RNA Polymerase II can Fine- tune the Phosphatase Activity of Ssu72.Novel Modifications on C-terminal Domain of RNA Polymerase II can Fine- tune the Phosphatase Activity of Ssu72.
Template:ABSTRACT PUBMED 23844594
FunctionFunction
[SYMPK_DROME] Component of a protein complex required for cotranscriptional processing of 3'-ends of polyadenylated and histone pre-mRNA.[1] [2]
About this StructureAbout this Structure
4imi is a 5 chain structure with sequence from Drosophila melanogaster. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Luo Y, Yogesha SD, Cannon JR, Yan W, Ellington AD, Brodbelt JS, Zhang Y. Novel Modifications on C-terminal Domain of RNA Polymerase II Can Fine-tune the Phosphatase Activity of Ssu72. ACS Chem Biol. 2013 Jul 23. PMID:23844594 doi:10.1021/cb400229c
- ↑ Wagner EJ, Burch BD, Godfrey AC, Salzler HR, Duronio RJ, Marzluff WF. A genome-wide RNA interference screen reveals that variant histones are necessary for replication-dependent histone pre-mRNA processing. Mol Cell. 2007 Nov 30;28(4):692-9. PMID:18042462 doi:10.1016/j.molcel.2007.10.009
- ↑ Sullivan KD, Steiniger M, Marzluff WF. A core complex of CPSF73, CPSF100, and Symplekin may form two different cleavage factors for processing of poly(A) and histone mRNAs. Mol Cell. 2009 May 15;34(3):322-32. doi: 10.1016/j.molcel.2009.04.024. PMID:19450530 doi:10.1016/j.molcel.2009.04.024