4jph: Difference between revisions
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{{STRUCTURE_4jph| PDB=4jph | SCENE= }} | {{STRUCTURE_4jph| PDB=4jph | SCENE= }} | ||
===Crystal structure of Protein Related to DAN and Cerberus (PRDC)=== | ===Crystal structure of Protein Related to DAN and Cerberus (PRDC)=== | ||
{{ABSTRACT_PUBMED_23850456}} | |||
==Function== | ==Function== | ||
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==Reference== | ==Reference== | ||
<references group="xtra"/><references/> | <ref group="xtra">PMID:023850456</ref><references group="xtra"/><references/> | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
[[Category: Deng, X.]] | [[Category: Deng, X.]] | ||
Revision as of 22:09, 7 August 2013
Crystal structure of Protein Related to DAN and Cerberus (PRDC)Crystal structure of Protein Related to DAN and Cerberus (PRDC)
Template:ABSTRACT PUBMED 23850456
FunctionFunction
[GREM2_MOUSE] Cytokine that inhibits the activity of BMP2 and BMP4 in a dose-dependent manner. Antagonized BMP4-induced suppression of progesterone production in granulosa cells.[1]
About this StructureAbout this Structure
4jph is a 4 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Nolan K, Kattamuri C, Luedeke DM, Deng X, Jagpal A, Zhang F, Linhardt RJ, Kenny AP, Zorn AM, Thompson TB. Structure of Protein Related to Dan and Cerberus: Insights into the Mechanism of Bone Morphogenetic Protein Antagonism. Structure. 2013 Jul 9. pii: S0969-2126(13)00206-2. doi:, 10.1016/j.str.2013.06.005. PMID:23850456 doi:10.1016/j.str.2013.06.005
- ↑ Sudo S, Avsian-Kretchmer O, Wang LS, Hsueh AJ. Protein related to DAN and cerberus is a bone morphogenetic protein antagonist that participates in ovarian paracrine regulation. J Biol Chem. 2004 May 28;279(22):23134-41. Epub 2004 Mar 23. PMID:15039429 doi:10.1074/jbc.M402376200