Arginine repressor: Difference between revisions
No edit summary |
Michal Harel (talk | contribs) No edit summary |
||
| Line 7: | Line 7: | ||
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
===Arginine repressor=== | |||
[[1b4a]] – GsArgR – ''Geobacillus stearothermophilus'' <br /> | [[1b4a]] – GsArgR – ''Geobacillus stearothermophilus'' <br /> | ||
| Line 16: | Line 16: | ||
[[3lap]] – MtArgR + DNA + canavanine <br /> | [[3lap]] – MtArgR + DNA + canavanine <br /> | ||
===Arginine repressor N terminal=== | |||
[[1aoy]] – EcArgR N terminal - ''Escherichia coli'' - NMR<br /> | [[1aoy]] – EcArgR N terminal - ''Escherichia coli'' - NMR<br /> | ||
| Line 22: | Line 22: | ||
[[2p5l]] – BsArgR N terminal + DNA <br /> | [[2p5l]] – BsArgR N terminal + DNA <br /> | ||
===Arginine repressor C terminal=== | |||
[[1xxc]] – EcArgR C terminal <br /> | [[1xxc]] – EcArgR C terminal <br /> | ||
Revision as of 13:31, 14 August 2014
<StructureSection load='3laj' size='350' side='right' caption='Structure of arginine repressor hexamer complex with DNA and arginine (PDB entry 3laj)' scene=>
Arginine repressor (ArgR) is a prokaryotic repressor which regulates the arginine deiminase pathway. In this pathway, arginine is metabolized to form ammonia, CO2 and ATP. The ArgR releases the expression of the arginine deiminase pathway in the presence of arginine. The genes controlled by ArgR are not found in a single operon. While repressors are usually active as dimers, ArgR is a hexamer and binds to 2 palindromic DNA sites. The structure of ArgR shows a DNA-binding domain at the N-terminal and a C-terminal domain which contains the intersubunit interaction sites and the Arg binding site.
3D structures of arginine repressor3D structures of arginine repressor
Updated on 14-August-2014
Arginine repressorArginine repressor
1b4a – GsArgR – Geobacillus stearothermophilus
1f9n – BsArgR – Bacillus subtilis
3v4g – ArgR – Vibrio vulnificus
3ere – MtArgR + DNA – Mycobacterium tuberculosis
3fhz, 3laj – MtArgR + DNA + Arg
3lap – MtArgR + DNA + canavanine
Arginine repressor N terminalArginine repressor N terminal
1aoy – EcArgR N terminal - Escherichia coli - NMR
1b4b – BsArgR N terminal
2p5l – BsArgR N terminal + DNA
Arginine repressor C terminalArginine repressor C terminal
1xxc – EcArgR C terminal
2p5k – GsArgR C terminal
3bue – MtArgR C terminal
1xxb – EcArgR C terminal + Arg
1xxa, 1xxb – EcArgR C terminal + Arg
2p5m – BsArgR C terminal (mutant) + Arg
2zfz, 3cag – MtArgR C terminal + Arg