Opioid receptor: Difference between revisions
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<StructureSection load='4djh' size='350' side='right' caption='Structure of κ-opioid receptor complex with opioid antagonist, citric acid, PEG and octadec-enoate derivative (PDB entry [[4djh]])' scene=''> | <StructureSection load='4djh' size='350' side='right' caption='Structure of κ-opioid receptor complex with opioid antagonist, citric acid, PEG and octadec-enoate derivative (PDB entry [[4djh]])' scene=''> | ||
'''Opioid receptor''' (OpR) is a G protein-coupled receptor with opioids as ligands. OpR types are classified according to the ligands which bind to them. The '''μ-opioid receptor''' binds morphine | '''Opioid receptor''' (OpR) is a G protein-coupled receptor with opioids as ligands. OpR types are classified according to the ligands which bind to them.<br /> | ||
* The '''μ-opioid receptor''' binds morphine. For more details on μ-opioid receptor see [[Mu Opioid Receptor Bound to a Morphinan Antagonist]].<br /> | |||
* The '''κ-opioid receptor''' binds opium-type ligands.<br /> | |||
* The '''δ-opioid receptor''' binds enkephalins. | |||
==3D structures of opioid receptor== | ==3D structures of opioid receptor== | ||
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
===δ-opioid receptor=== | |||
[[4ej4]] – mOpR + naltrindole - mouse <br /> | [[4ej4]] – mOpR + naltrindole - mouse <br /> | ||
===κ-opioid receptor=== | |||
[[4djh]] – hOpR + opioid antagonist - human <br /> | [[4djh]] – hOpR + opioid antagonist - human <br /> | ||
===Nociceptin/orphanin FQ opioid receptor=== | |||
[[4ea3]] – hOpR + peptide mimetic <br /> | [[4ea3]] – hOpR + peptide mimetic <br /> | ||
===μ-opioid receptor'=== | |||
[[4dkl]] – mOpR + opioid antagonist <br /> | [[4dkl]] – mOpR + opioid antagonist <br /> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 12:24, 19 August 2014
<StructureSection load='4djh' size='350' side='right' caption='Structure of κ-opioid receptor complex with opioid antagonist, citric acid, PEG and octadec-enoate derivative (PDB entry 4djh)' scene=>
Opioid receptor (OpR) is a G protein-coupled receptor with opioids as ligands. OpR types are classified according to the ligands which bind to them.
- The μ-opioid receptor binds morphine. For more details on μ-opioid receptor see Mu Opioid Receptor Bound to a Morphinan Antagonist.
- The κ-opioid receptor binds opium-type ligands.
- The δ-opioid receptor binds enkephalins.
3D structures of opioid receptor3D structures of opioid receptor
Updated on 19-August-2014
δ-opioid receptorδ-opioid receptor
4ej4 – mOpR + naltrindole - mouse
κ-opioid receptorκ-opioid receptor
4djh – hOpR + opioid antagonist - human
Nociceptin/orphanin FQ opioid receptorNociceptin/orphanin FQ opioid receptor
4ea3 – hOpR + peptide mimetic
μ-opioid receptor'μ-opioid receptor'
4dkl – mOpR + opioid antagonist