Opioid receptor: Difference between revisions

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[[4dkl]] – mOpR + opioid antagonist  <br />
[[4dkl]] – mOpR + opioid antagonist  <br />
[[Category:Topic Page]]

Revision as of 11:50, 16 July 2013

<StructureSection load='4djh' size='350' side='right' caption='Structure of κ-opioid receptor complex with opioid antagonist, citric acid, PEG and octadec-enoate derivative (PDB entry 4djh)' scene=>

Opioid receptor (OpR) is a G protein-coupled receptor with opioids as ligands. OpR types are classified according to the ligands which bind to them. The μ-opioid receptor binds morphine; The κ-opioid receptor binds opium-type ligands; The δ-opioid receptor binds enkephalins. For more details on μ-opioid receptor see Mu Opioid Receptor Bound to a Morphinan Antagonist.

3D structures of opioid receptor3D structures of opioid receptor

Updated on 16-July-2013

δ-opioid receptor

4ej4 – mOpR + naltrindole - mouse

κ-opioid receptor

4djh – hOpR + opioid antagonist - human

Nociceptin/orphanin FQ opioid receptor

4ea3 – hOpR + peptide mimetic

μ-opioid receptor

4dkl – mOpR + opioid antagonist

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman, Karsten Theis