4lfx: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4lfx|  PDB=4lfx  |  SCENE=  }}
===X-ray structure of the adduct between hen egg white lysozyme and Auoxo6, a dinuclear gold(III) complex with -dioxo bridges linking the two metal centers===
{{ABSTRACT_PUBMED_24045294}}


The entry 4lfx is ON HOLD until Paper Publication
==Function==
[[http://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK]] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>  


Authors: Vergara, A., Merlino, A.
==About this Structure==
[[4lfx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LFX OCA].  


Description: X-ray structure of the adduct between hen egg white lysozyme and Auoxo6, a dinuclear gold(III) complexes with -dioxo bridges linking the two metal centers
==Reference==
<ref group="xtra">PMID:024045294</ref><references group="xtra"/><references/>
[[Category: Gallus gallus]]
[[Category: Lysozyme]]
[[Category: Merlino, A.]]
[[Category: Vergara, A.]]
[[Category: Hydrolase]]

Revision as of 10:25, 2 October 2013

Template:STRUCTURE 4lfx

X-ray structure of the adduct between hen egg white lysozyme and Auoxo6, a dinuclear gold(III) complex with -dioxo bridges linking the two metal centersX-ray structure of the adduct between hen egg white lysozyme and Auoxo6, a dinuclear gold(III) complex with -dioxo bridges linking the two metal centers

Template:ABSTRACT PUBMED 24045294

FunctionFunction

[LYSC_CHICK] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.[1]

About this StructureAbout this Structure

4lfx is a 1 chain structure with sequence from Gallus gallus. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Messori L, Scaletti F, Massai L, Cinellu MA, Gabbiani C, Vergara A, Merlino A. The mode of action of anticancer gold-based drugs: a structural perspective. Chem Commun (Camb). 2013 Sep 18. PMID:24045294 doi:10.1039/c3cc46400h
  1. Maehashi K, Matano M, Irisawa T, Uchino M, Kashiwagi Y, Watanabe T. Molecular characterization of goose- and chicken-type lysozymes in emu (Dromaius novaehollandiae): evidence for extremely low lysozyme levels in emu egg white. Gene. 2012 Jan 15;492(1):244-9. doi: 10.1016/j.gene.2011.10.021. Epub 2011 Oct, 25. PMID:22044478 doi:10.1016/j.gene.2011.10.021

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