4l2o: Difference between revisions
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{{STRUCTURE_4l2o| PDB=4l2o | SCENE= }} | |||
===Crystal structure of human ALDH3A1 with its selective inhibitor 1-(4-fluorophenyl)sulfonyl-2-methylbenzimidazole=== | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/AL3A1_HUMAN AL3A1_HUMAN]] ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. This protein preferentially oxidizes aromatic aldehyde substrates. It may play a role in the oxidation of toxic aldehydes. | |||
==About this Structure== | |||
[[4l2o]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L2O OCA]. | |||
[[Category: Hurley, T D.]] | |||
[[Category: Parajuli, B.]] | |||
[[Category: Catalyzes benzaldehyde]] | |||
[[Category: Dehydrogenase]] | |||
[[Category: Nadp+ binding]] | |||
[[Category: Oxidoreductase-inhibitor complex]] | |||
[[Category: Rossman fold]] | |||
Revision as of 10:48, 29 January 2014
Crystal structure of human ALDH3A1 with its selective inhibitor 1-(4-fluorophenyl)sulfonyl-2-methylbenzimidazoleCrystal structure of human ALDH3A1 with its selective inhibitor 1-(4-fluorophenyl)sulfonyl-2-methylbenzimidazole
FunctionFunction
[AL3A1_HUMAN] ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. This protein preferentially oxidizes aromatic aldehyde substrates. It may play a role in the oxidation of toxic aldehydes.
About this StructureAbout this Structure
4l2o is a 4 chain structure. Full crystallographic information is available from OCA.