4lf3: Difference between revisions

Revision as of 11:29, 13 November 2013

Inhibitory Mechanism of an Allosteric Antibody Targeting the Glucagon ReceptorInhibitory Mechanism of an Allosteric Antibody Targeting the Glucagon Receptor

FunctionFunction

[GLR_HUMAN] This is a receptor for glucagon which plays a central role in regulating the level of blood glucose by controlling the rate of hepatic glucose production and insulin secretion. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system.

About this StructureAbout this Structure

4lf3 is a 6 chain structure. Full crystallographic information is available from OCA.

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+{{STRUCTURE_4lf3|  PDB=4lf3  |  SCENE=  }}
+===Inhibitory Mechanism of an Allosteric Antibody Targeting the Glucagon Receptor===
-The entry 4lf3 is ON HOLD
+==Function==
+[[http://www.uniprot.org/uniprot/GLR_HUMAN GLR_HUMAN]] This is a receptor for glucagon which plays a central role in regulating the level of blood glucose by controlling the rate of hepatic glucose production and insulin secretion. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system.
-Authors: Murray, J.M., Mukund, S.
+==About this Structure==
+[[4lf3]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LF3 OCA].
-Description: Inhibitory Mechanism of an Allosteric Antibody Targeting the Glucagon Receptor
+[[Category: Mukund, S.]]
+[[Category: Murray, J M.]]
+[[Category: Fab fragment]]
+[[Category: Gcgr]]
+[[Category: Immune system]]