Sorting nexin

<StructureSection load='3dyt' size='350' side='right' caption='Structure of human sorting nexin-9 PX domain complex with sulfate (PDB entry 3dyt)' scene=>

Sorting nexins (SNX) are proteins which enhance membrane association via their lipid-binding PX domain or via protein-protein association. The PX domain contains a phospholipid-binding motif.

3D structures of sorting nexin3D structures of sorting nexin

Updated on 02-July-2013

SNX-1

2i4k – hSNX PX domain - NMR

SNX-3

1ocs – ySNX PX domain – yeast
1ocu – ySNX PX domain + phosphatidylinositol-3-phosphate
2yps – hSNX PX domain

SNX-5

3hpb, 3hpc – rSNX PX domain – rat

SNX-7

3iq2 – hSNX PX domain

SNX-9

2enm – SNX SH3 domain – mouse - NMR
2rai, 2raj, 2rak, 3dyt, 3dyu – hSNX PX-BAR domain
3lge – SNX residues 152-182 + aldolase – rabbit

SNX-11

4ikb, 4ikd – hSNX PX domain

SNX-12

2csk – hSNX PX domain

SNX-14

4bgj – hSNX PX domain

SNX-17

3fog, 3lui – hSNX PX domain
4gxb – hSNX FERM domain + P-selectin NPXY motif

SNX-22

2ett – hSNX PX domain - NMR

SNX-24

4az9 – hSNX PX domain

SNX-27

3qdo, 3qe1 – rSNX PDZ domain/GIRK3 C terminal
3qgl – rSNX PDZ domain + GIRK3 C terminal
4has – hSNX PX domain

SNX-33

4akv – hSNX PH-BAR domain