2i0e: Difference between revisions

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[[Image:2i0e.gif|left|200px]]<br /><applet load="2i0e" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2i0e.gif|left|200px]]
caption="2i0e, resolution 2.60&Aring;" />
 
'''Structure of catalytic domain of human protein kinase C beta II complexed with a bisindolylmaleimide inhibitor'''<br />
{{Structure
|PDB= 2i0e |SIZE=350|CAPTION= <scene name='initialview01'>2i0e</scene>, resolution 2.60&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=PDS:3-{1-[3-(DIMETHYLAMINO)PROPYL]-2-METHYL-1H-INDOL-3-YL}-4-(2-METHYL-1H-INDOL-3-YL)-1H-PYRROLE-2,5-DIONE'>PDS</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Protein_kinase_C Protein kinase C], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.13 2.7.11.13]
|GENE=
}}
 
'''Structure of catalytic domain of human protein kinase C beta II complexed with a bisindolylmaleimide inhibitor'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2I0E is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=PDS:'>PDS</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Protein_kinase_C Protein kinase C], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.13 2.7.11.13] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I0E OCA].  
2I0E is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I0E OCA].  


==Reference==
==Reference==
Structure of the catalytic domain of human protein kinase C beta II complexed with a bisindolylmaleimide inhibitor., Grodsky N, Li Y, Bouzida D, Love R, Jensen J, Nodes B, Nonomiya J, Grant S, Biochemistry. 2006 Nov 28;45(47):13970-81. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17115692 17115692]
Structure of the catalytic domain of human protein kinase C beta II complexed with a bisindolylmaleimide inhibitor., Grodsky N, Li Y, Bouzida D, Love R, Jensen J, Nodes B, Nonomiya J, Grant S, Biochemistry. 2006 Nov 28;45(47):13970-81. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17115692 17115692]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Protein kinase C]]
[[Category: Protein kinase C]]
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[[Category: serine/threonine protein kinase]]
[[Category: serine/threonine protein kinase]]


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