2hck: Difference between revisions

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[[Image:2hck.gif|left|200px]]<br /><applet load="2hck" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2hck.gif|left|200px]]
caption="2hck, resolution 3.0&Aring;" />
 
'''SRC FAMILY KINASE HCK-QUERCETIN COMPLEX'''<br />
{{Structure
|PDB= 2hck |SIZE=350|CAPTION= <scene name='initialview01'>2hck</scene>, resolution 3.0&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene> and <scene name='pdbligand=QUE:3,5,7,3',4'-PENTAHYDROXYFLAVONE'>QUE</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Transferase Transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 and 2.7.10.2 2.7.10.1 and 2.7.10.2]
|GENE= HUMAN HCK ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''SRC FAMILY KINASE HCK-QUERCETIN COMPLEX'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2HCK is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=CA:'>CA</scene> and <scene name='pdbligand=QUE:'>QUE</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. The following page contains interesting information on the relation of 2HCK with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb43_1.html Src Tyrosine Kinase]]. Active as [http://en.wikipedia.org/wiki/Transferase Transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 and 2.7.10.2 2.7.10.1 and 2.7.10.2] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HCK OCA].  
2HCK is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. The following page contains interesting information on the relation of 2HCK with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb43_1.html Src Tyrosine Kinase]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HCK OCA].  


==Reference==
==Reference==
Crystal structure of the Src family tyrosine kinase Hck., Sicheri F, Moarefi I, Kuriyan J, Nature. 1997 Feb 13;385(6617):602-9. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9024658 9024658]
Crystal structure of the Src family tyrosine kinase Hck., Sicheri F, Moarefi I, Kuriyan J, Nature. 1997 Feb 13;385(6617):602-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9024658 9024658]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: transferase]]
[[Category: transferase]]


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