4knm: Difference between revisions

Revision as of 10:47, 6 November 2013

[CAH13_HUMAN] Reversible hydration of carbon dioxide.

4knm is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

↑ Capkauskaite E, Zubriene A, Smirnov A, Torresan J, Kisonaite M, Kazokaite J, Gylyte J, Michailoviene V, Jogaite V, Manakova E, Grazulis S, Tumkevicius S, Matulis D. Benzenesulfonamides with pyrimidine moiety as inhibitors of human carbonic anhydrases I, II, VI, VII, XII, and XIII. Bioorg Med Chem. 2013 Nov 15;21(22):6937-47. doi: 10.1016/j.bmc.2013.09.029. Epub, 2013 Sep 20. PMID:24103428 doi:http://dx.doi.org/10.1016/j.bmc.2013.09.029

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-'''Unreleased structure'''
+{{STRUCTURE_4knm|  PDB=4knm  |  SCENE=  }}
+===Crystal structure of human carbonic anhydrase isozyme XIII with 2-Chloro-4-{[(4,6-dimethylpyrimidin-2-yl)sulfanyl]acetyl}benzenesulfonamide===
+{{ABSTRACT_PUBMED_24103428}}
-The entry 4knm is ON HOLD
+==Function==
+[[http://www.uniprot.org/uniprot/CAH13_HUMAN CAH13_HUMAN]] Reversible hydration of carbon dioxide.
-Authors: Smirnov, A., Manakova, E., Grazulis, S.
+==About this Structure==
+[[4knm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KNM OCA].
-Description: Crystal structure of human carbonic anhydrase isozyme XIII with 2-Chloro-4-{[(4,6-dimethylpyrimidin-2-yl)sulfanyl]acetyl}benzenesulfonamide
+==Reference==
+<ref group="xtra">PMID:024103428</ref><references group="xtra"/><references/>
+[[Category: Carbonate dehydratase]]
+[[Category: Homo sapiens]]
+[[Category: Grazulis, S.]]
+[[Category: Manakova, E.]]
+[[Category: Smirnov, A.]]
+[[Category: Benzenesulfonamide]]
+[[Category: Carbonic anhydrase]]
+[[Category: Drug design]]
+[[Category: Lyase-lyase inhibitor complex]]
+[[Category: Metal-binding]]