2h11: Difference between revisions
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[[Image:2h11.gif|left|200px]] | [[Image:2h11.gif|left|200px]] | ||
'''Amino-terminal Truncated Thiopurine S-Methyltransferase Complexed with S-Adenosyl-L-Homocysteine''' | {{Structure | ||
|PDB= 2h11 |SIZE=350|CAPTION= <scene name='initialview01'>2h11</scene>, resolution 1.89Å | |||
|SITE= | |||
|LIGAND= <scene name='pdbligand=SCN:THIOCYANATE+ION'>SCN</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene> and <scene name='pdbligand=B3P:2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>B3P</scene> | |||
|ACTIVITY= [http://en.wikipedia.org/wiki/Thiopurine_S-methyltransferase Thiopurine S-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.67 2.1.1.67] | |||
|GENE= TPMT ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | |||
}} | |||
'''Amino-terminal Truncated Thiopurine S-Methyltransferase Complexed with S-Adenosyl-L-Homocysteine''' | |||
==Disease== | ==Disease== | ||
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==About this Structure== | ==About this Structure== | ||
2H11 is a [ | 2H11 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H11 OCA]. | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: binary protein-cofactor complex]] | [[Category: binary protein-cofactor complex]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:11:18 2008'' | ||
Revision as of 18:11, 20 March 2008
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| , resolution 1.89Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | , and | ||||||
| Gene: | TPMT (Homo sapiens) | ||||||
| Activity: | Thiopurine S-methyltransferase, with EC number 2.1.1.67 | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Amino-terminal Truncated Thiopurine S-Methyltransferase Complexed with S-Adenosyl-L-Homocysteine
DiseaseDisease
Known disease associated with this structure: 6-mercaptopurine sensitivity OMIM:[187680]
About this StructureAbout this Structure
2H11 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Page seeded by OCA on Thu Mar 20 17:11:18 2008