2gv7: Difference between revisions
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[[Image:2gv7.gif|left|200px]] | [[Image:2gv7.gif|left|200px]] | ||
'''Structure of Matriptase in Complex with Inhibitor CJ-672''' | {{Structure | ||
|PDB= 2gv7 |SIZE=350|CAPTION= <scene name='initialview01'>2gv7</scene>, resolution 2.2Å | |||
|SITE= | |||
|LIGAND= <scene name='pdbligand=672:(S)-4-(4-(3-(3-CARBAMIMIDOYLPHENYL)-2-(2,4,6-TRIISOPROPYLPHENYLSULFONAMIDO)PROPANOYL)PIPERAZINE-1-CARBONYL)PIPERIDINE-1-CARBOXIMIDAMIDE'>672</scene> | |||
|ACTIVITY= | |||
|GENE= ST14 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | |||
}} | |||
'''Structure of Matriptase in Complex with Inhibitor CJ-672''' | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
2GV7 is a [ | 2GV7 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GV7 OCA]. | ||
==Reference== | ==Reference== | ||
Secondary amides of sulfonylated 3-amidinophenylalanine. New potent and selective inhibitors of matriptase., Steinmetzer T, Schweinitz A, Sturzebecher A, Donnecke D, Uhland K, Schuster O, Steinmetzer P, Muller F, Friedrich R, Than ME, Bode W, Sturzebecher J, J Med Chem. 2006 Jul 13;49(14):4116-26. PMID:[http:// | Secondary amides of sulfonylated 3-amidinophenylalanine. New potent and selective inhibitors of matriptase., Steinmetzer T, Schweinitz A, Sturzebecher A, Donnecke D, Uhland K, Schuster O, Steinmetzer P, Muller F, Friedrich R, Than ME, Bode W, Sturzebecher J, J Med Chem. 2006 Jul 13;49(14):4116-26. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16821772 16821772] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: matriptase]] | [[Category: matriptase]] | ||
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