2gtm: Difference between revisions

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OCA

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-[[Image:2gtm.gif|left|200px]]<br /><applet load="2gtm" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:2gtm.gif|left|200px]]
-caption="2gtm, resolution 1.90&Aring;" />
-'''Mutated Mouse P38 MAP Kinase Domain in complex with Inhibitor PG-892579'''<br />
+ {{Structure
+|PDB= 2gtm |SIZE=350|CAPTION= <scene name='initialview01'>2gtm</scene>, resolution 1.90&Aring;
+|SITE=
+|LIGAND= <scene name='pdbligand=LID:8-(2-CHLOROPHENYLAMINO)-2-(2,6-DIFLUOROPHENYLAMINO)-9-ETHYL-9H-PURINE-1,7-DIIUM'>LID</scene>
+|ACTIVITY= [http://en.wikipedia.org/wiki/Mitogen-activated_protein_kinase Mitogen-activated protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.24 2.7.11.24]
+|GENE= Mapk14 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])
+}}
+'''Mutated Mouse P38 MAP Kinase Domain in complex with Inhibitor PG-892579'''
 ==Overview==
@@ Line 7: / Line 16: @@
 ==About this Structure==
-GTM is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] with <scene name='pdbligand=LID:'>LID</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Mitogen-activated_protein_kinase Mitogen-activated protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.24 2.7.11.24] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GTM OCA].
+GTM is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GTM OCA].
 ==Reference==
-The development of novel C-2, C-8, and N-9 trisubstituted purines as inhibitors of TNF-alpha production., Sabat M, Vanrens JC, Clark MP, Brugel TA, Maier J, Bookland RG, Laufersweiler MJ, Laughlin SK, Golebiowski A, De B, Hsieh LC, Walter RL, Mekel MJ, Janusz MJ, Bioorg Med Chem Lett. 2006 Aug 15;16(16):4360-5. Epub 2006 Jun 5. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16750367 16750367]
+The development of novel C-2, C-8, and N-9 trisubstituted purines as inhibitors of TNF-alpha production., Sabat M, Vanrens JC, Clark MP, Brugel TA, Maier J, Bookland RG, Laufersweiler MJ, Laughlin SK, Golebiowski A, De B, Hsieh LC, Walter RL, Mekel MJ, Janusz MJ, Bioorg Med Chem Lett. 2006 Aug 15;16(16):4360-5. Epub 2006 Jun 5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16750367 16750367]
 [[Category: Mitogen-activated protein kinase]]
 [[Category: Mus musculus]]
@@ Line 23: / Line 32: @@
 [[Category: p38]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:35:15 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:08:54 2008''