2lez: Difference between revisions

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-{{STRUCTURE_2lez|  PDB=2lez  |  SCENE=  }}
+==Solution NMR structure of N-terminal domain of Salmonella effector protein PipB2. Northeast structural genomics consortium (NESG) target stt318a==
-===Solution NMR structure of N-terminal domain of Salmonella effector protein PipB2. Northeast structural genomics consortium (NESG) target stt318a===
+<StructureSection load='2lez' size='340' side='right' caption='[[2lez]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
+== Structural highlights ==
-==Function==
+<table><tr><td colspan='2'>[[2lez]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium Salmonella enterica subsp. enterica serovar typhimurium]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LEZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LEZ FirstGlance]. <br>
-[[http://www.uniprot.org/uniprot/PIPB2_SALTY PIPB2_SALTY]] Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. Involved in the reorganization of late endosome/lysosome (LE/Lys) compartments in mammalian cells. Necessary and sufficient to link kinesin-1 onto the Salmonella-containing vacuole (SCV) membrane. Required for centrifugal extension of lysosomal glycoprotein-rich membrane tubules, known as Salmonella-induced filaments (Sifs), away from the SCV and toward the cell periphery. Required for virulence, but not for intracellular survival and replication in phagocytic cells.<ref>PMID:12864852</ref> <ref>PMID:15987736</ref> <ref>PMID:16938850</ref>
+</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pipB2, STM2780 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=90371 Salmonella enterica subsp. enterica serovar Typhimurium])</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lez FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lez OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2lez RCSB], [http://www.ebi.ac.uk/pdbsum/2lez PDBsum]</span></td></tr>
-==About this Structure==
+</table>
-[[2lez]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium Salmonella enterica subsp. enterica serovar typhimurium]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LEZ OCA].
+__TOC__
+</StructureSection>
-==Reference==
-<references group="xtra"/><references/>
 [[Category: Salmonella enterica subsp. enterica serovar typhimurium]]
-[[Category: Arrowsmith, C.]]
+[[Category: Arrowsmith, C]]
-[[Category: Daniels, C.]]
+[[Category: Daniels, C]]
-[[Category: Garcia, M.]]
+[[Category: Garcia, M]]
-[[Category: Houliston, S.]]
+[[Category: Houliston, S]]
-[[Category: Lemak, A.]]
+[[Category: Lemak, A]]
-[[Category: Montelione, G T.]]
+[[Category: Montelione, G T]]
-[[Category: NESG, Northeast Structural Genomics Consortium.]]
+[[Category: Structural genomic]]
-[[Category: Savchenko, A.]]
+[[Category: Savchenko, A]]
-[[Category: Yee, A.]]
+[[Category: Yee, A]]
 [[Category: Bacterial effector]]
 [[Category: Nesg]]
-[[Category: Northeast structural genomics consortium]]
 [[Category: Signaling protein]]
-[[Category: Structural genomic]]
 [[Category: Virulence factor]]