1vtn: Difference between revisions

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-{{STRUCTURE_1vtn|  PDB=1vtn  |  SCENE=  }}
+==CO-CRYSTAL STRUCTURE OF THE HNF-3/FORK HEAD DNA-RECOGNITION MOTIF RESEMBLES HISTONE H5==
-===CO-CRYSTAL STRUCTURE OF THE HNF-3/FORK HEAD DNA-RECOGNITION MOTIF RESEMBLES HISTONE H5===
+<StructureSection load='1vtn' size='340' side='right' caption='[[1vtn]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
-{{ABSTRACT_PUBMED_8332212}}
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1vtn]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VTN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1VTN FirstGlance]. <br>
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1vtn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vtn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1vtn RCSB], [http://www.ebi.ac.uk/pdbsum/1vtn PDBsum]</span></td></tr>
+</table>
+<div style="background-color:#fffaf0;">
+== Publication Abstract from PubMed ==
+The three-dimensional structure of an HNF-3/fork head DNA-recognition motif complexed with DNA has been determined by X-ray crystallography at 2.5 A resolution. This alpha/beta protein binds B-DNA as a monomer, through interactions with the DNA backbone and through both direct and water-mediated major and minor groove base contacts, inducing a 13 degrees bend. The transcription factor fold is very similar to the structure of histone H5. In its amino-terminal half, three alpha-helices adopt a compact structure that presents the third helix to the major groove. The remainder of the protein includes a twisted, antiparallel beta-structure and random coil that interacts with the minor groove.
-==About this Structure==
+Co-crystal structure of the HNF-3/fork head DNA-recognition motif resembles histone H5.,Clark KL, Halay ED, Lai E, Burley SK Nature. 1993 Jul 29;364(6436):412-20. PMID:8332212<ref>PMID:8332212</ref>
-[[1vtn]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VTN OCA].
-==Reference==
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-<ref group="xtra">PMID:008332212</ref><references group="xtra"/><references/>
+</div>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
 [[Category: Homo sapiens]]
-[[Category: Burley, S K.]]
+[[Category: Burley, S K]]
-[[Category: Clark, K L.]]
+[[Category: Clark, K L]]
-[[Category: Halay, E D.]]
+[[Category: Halay, E D]]
-[[Category: Lai, E.]]
+[[Category: Lai, E]]
 [[Category: Double helix]]
 [[Category: Protein-dna complex]]
 [[Category: Transcription-dna complex]]