3ps9: Difference between revisions
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{{STRUCTURE_3ps9| PDB=3ps9 | SCENE= }} | {{STRUCTURE_3ps9| PDB=3ps9 | SCENE= }} | ||
===Crystal structure of MnmC from E. coli=== | ===Crystal structure of MnmC from E. coli=== | ||
{{ABSTRACT_PUBMED_23617613}} | |||
==Function== | ==Function== | ||
[[http://www.uniprot.org/uniprot/ | [[http://www.uniprot.org/uniprot/C6ELC9_ECOBD C6ELC9_ECOBD]] Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity).[SAAS:SAAS006076_004_060760][HAMAP-Rule:MF_01102] | ||
==About this Structure== | ==About this Structure== | ||
[[3ps9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/ | [[3ps9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_bl21 Escherichia coli bl21]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PS9 OCA]. | ||
[[Category: Escherichia coli]] | |||
==Reference== | |||
<ref group="xtra">PMID:023617613</ref><references group="xtra"/><references/> | |||
[[Category: Escherichia coli bl21]] | |||
[[Category: Almo, S C.]] | [[Category: Almo, S C.]] | ||
[[Category: Kim, J.]] | [[Category: Kim, J.]] | ||
Revision as of 11:27, 21 August 2013
Crystal structure of MnmC from E. coliCrystal structure of MnmC from E. coli
Template:ABSTRACT PUBMED 23617613
FunctionFunction
[C6ELC9_ECOBD] Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity).[SAAS:SAAS006076_004_060760][HAMAP-Rule:MF_01102]
About this StructureAbout this Structure
3ps9 is a 1 chain structure with sequence from Escherichia coli bl21. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Kim J, Almo SC. Structural basis for hypermodification of the wobble uridine in tRNA by bifunctional enzyme MnmC. BMC Struct Biol. 2013 Apr 24;13:5. doi: 10.1186/1472-6807-13-5. PMID:23617613 doi:10.1186/1472-6807-13-5