Complement Regulator-Acquiring Surface Protein: Difference between revisions

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Revision as of 04:58, 5 May 2013 view source Dipanshu Walia (talk \| contribs) 44 edits No edit summary ← Older edit		Revision as of 04:59, 5 May 2013 view source Dipanshu Walia (talk \| contribs) 44 edits No edit summary Newer edit →
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	=== '''Other Potential Binding Sites''' ===		=== '''Other Potential Binding Sites''' ===

	Additional studies were done to investigate the FH and FHL-1 binding sites on the protein. As with previous research, areas of high conservation were investigated due to their relationship with upholding the structure and function of the protein (Cordes ~~et al. 2010)~~. Researchers examined highly conserved areas of amino acid sequences along the <scene name='SB2013_L01gr6/Pocket_region/1'>cleft region</scene> of the protein. They saw that the majority of these regions clustered on a highly-exposed region of the protein.		Additional studies were done to investigate the FH and FHL-1 binding sites on the protein. As with previous research, areas of high conservation were investigated due to their relationship with upholding the structure and function of the protein <ref name="Cordes 06">PMID: 16530476</ref>. Researchers examined highly conserved areas of amino acid sequences along the <scene name='SB2013_L01gr6/Pocket_region/1'>cleft region</scene> of the protein. They saw that the majority of these regions clustered on a highly-exposed region of the protein.