2fst: Difference between revisions

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[[Image:2fst.jpg|left|200px]]<br /><applet load="2fst" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2fst.jpg|left|200px]]
caption="2fst, resolution 1.45&Aring;" />
 
'''mitogen activated protein kinase p38alpha (D176A+F327L) activating mutant'''<br />
{{Structure
|PDB= 2fst |SIZE=350|CAPTION= <scene name='initialview01'>2fst</scene>, resolution 1.45&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=BOG:B-OCTYLGLUCOSIDE'>BOG</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1]
|GENE=
}}
 
'''mitogen activated protein kinase p38alpha (D176A+F327L) activating mutant'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2FST is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=BOG:'>BOG</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FST OCA].  
2FST is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FST OCA].  


==Reference==
==Reference==
Structures of p38alpha active mutants reveal conformational changes in L16 loop that induce autophosphorylation and activation., Diskin R, Lebendiker M, Engelberg D, Livnah O, J Mol Biol. 2007 Jan 5;365(1):66-76. Epub 2006 Aug 22. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17059827 17059827]
Structures of p38alpha active mutants reveal conformational changes in L16 loop that induce autophosphorylation and activation., Diskin R, Lebendiker M, Engelberg D, Livnah O, J Mol Biol. 2007 Jan 5;365(1):66-76. Epub 2006 Aug 22. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17059827 17059827]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: Livnah, O.]]
[[Category: Livnah, O.]]
[[Category: BOG]]
[[Category: BOG]]
[[Category: active mutants]]
[[Category: active mutant]]
[[Category: autophosphorylation]]
[[Category: autophosphorylation]]
[[Category: lipids]]
[[Category: lipid]]
[[Category: map kinase insertion]]
[[Category: map kinase insertion]]
[[Category: mitogen activated protein kinase]]
[[Category: mitogen activated protein kinase]]
[[Category: p38]]
[[Category: p38]]


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