2fst: Difference between revisions
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[[Image:2fst.jpg|left|200px]] | [[Image:2fst.jpg|left|200px]] | ||
'''mitogen activated protein kinase p38alpha (D176A+F327L) activating mutant''' | {{Structure | ||
|PDB= 2fst |SIZE=350|CAPTION= <scene name='initialview01'>2fst</scene>, resolution 1.45Å | |||
|SITE= | |||
|LIGAND= <scene name='pdbligand=BOG:B-OCTYLGLUCOSIDE'>BOG</scene> | |||
|ACTIVITY= [http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] | |||
|GENE= | |||
}} | |||
'''mitogen activated protein kinase p38alpha (D176A+F327L) activating mutant''' | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
2FST is a [ | 2FST is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FST OCA]. | ||
==Reference== | ==Reference== | ||
Structures of p38alpha active mutants reveal conformational changes in L16 loop that induce autophosphorylation and activation., Diskin R, Lebendiker M, Engelberg D, Livnah O, J Mol Biol. 2007 Jan 5;365(1):66-76. Epub 2006 Aug 22. PMID:[http:// | Structures of p38alpha active mutants reveal conformational changes in L16 loop that induce autophosphorylation and activation., Diskin R, Lebendiker M, Engelberg D, Livnah O, J Mol Biol. 2007 Jan 5;365(1):66-76. Epub 2006 Aug 22. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17059827 17059827] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Non-specific serine/threonine protein kinase]] | [[Category: Non-specific serine/threonine protein kinase]] | ||
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[[Category: Livnah, O.]] | [[Category: Livnah, O.]] | ||
[[Category: BOG]] | [[Category: BOG]] | ||
[[Category: active | [[Category: active mutant]] | ||
[[Category: autophosphorylation]] | [[Category: autophosphorylation]] | ||
[[Category: | [[Category: lipid]] | ||
[[Category: map kinase insertion]] | [[Category: map kinase insertion]] | ||
[[Category: mitogen activated protein kinase]] | [[Category: mitogen activated protein kinase]] | ||
[[Category: p38]] | [[Category: p38]] | ||
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