G1SecL05: Difference between revisions

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Revision as of 20:35, 2 May 2013 view source Supriya Kannan (talk \| contribs) 75 edits No edit summary ← Older edit		Revision as of 20:38, 2 May 2013 view source Supriya Kannan (talk \| contribs) 75 edits No edit summary Newer edit →
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	Although the LA-2- ospA complex induces a high reactivity of protective immune response for ''B. burgdorferi'', it lacks the broad specificity to encompass other genospecies of ''Borrelia''. In North America, Lyme borreliosis is caused by a single strain ''B.burgdorferi'', whereas in parts of Europe and Asia, a minimum of three strains, ''B. afzelli'', ''B. burgdorferi'', and ''B. garinii'' are involved in infecting humans<ref>PMID: 21217174</ref>. The lack of broad specificity in the LA-2- OspA complex is due to the presence of highly variable regions in ospA.		Although the LA-2- ospA complex induces a high reactivity of protective immune response for ''B. burgdorferi'', it lacks the broad specificity to encompass other genospecies of ''Borrelia''. In North America, Lyme borreliosis is caused by a single strain ''B.burgdorferi'', whereas in parts of Europe and Asia, a minimum of three strains, ''B. afzelli'', ''B. burgdorferi'', and ''B. garinii'' are involved in infecting humans<ref>PMID: 21217174</ref>. The lack of broad specificity in the LA-2- OspA complex is due to the presence of highly variable regions in ospA.


	===Trp-216===		===Trp-216===