G1SecL05: Difference between revisions

    Lyme disease, discovered in 1975<ref>PMID: 17160599</ref>, is a vector--borne disease caused by the inoculation of spirochete ''Borrelia'' into the skin by members of hard bodied ticks of the family ''Ixodidae''. Symptoms include arthritis at major joints, neurological problems such as reduced memory and poor ability to concentrate, and characteristic lesions ''erythema migan''s, more commonly known as the bull’s eye rash. A major outer surface membrane protein of ''Borrelia'', ospA, plays a key role in immunity against Lyme disease through its binding to the antibody LA-2 fab.               

[[Image:1fj1 .protein.jpg|280px|right|thumb| LA-2 ospA complex,[[1fj1]]]]

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