4hwp: Difference between revisions

Revision as of 07:13, 20 September 2013

[SYT_ECOLI] ThrS is also a translational repressor protein, it controls the translation of its own gene by binding to its mRNA.[HAMAP-Rule:MF_00184]

4hwp is a 2 chain structure with sequence from Escherichia coli k-12. Full crystallographic information is available from OCA.

↑ Teng M, Hilgers MT, Cunningham ML, Borchardt A, Locke JB, Abraham S, Haley G, Kwan BP, Hall C, Hough GW, Shaw KJ, Finn J. Identification of bacteria-selective threonyl-tRNA synthetase substrate inhibitors by structure-based design. J Med Chem. 2013 Feb 28;56(4):1748-60. doi: 10.1021/jm301756m. Epub 2013 Feb 12. PMID:23362938 doi:10.1021/jm301756m

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-'''Unreleased structure'''
+{{STRUCTURE_4hwp|  PDB=4hwp  |  SCENE=  }}
+===Crystal structure of E. coli Threonyl-tRNA synthetase bound to a novel inhibitor===
+{{ABSTRACT_PUBMED_23362938}}
-The entry 4hwp is ON HOLD  until Paper Publication
+==Function==
+[[http://www.uniprot.org/uniprot/SYT_ECOLI SYT_ECOLI]] ThrS is also a translational repressor protein, it controls the translation of its own gene by binding to its mRNA.[HAMAP-Rule:MF_00184]
-Authors: Hilgers, M.T.
+==About this Structure==
+[[4hwp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HWP OCA].
-Description: Crystal structure of E. coli Threonyl-tRNA synthetase bound to a novel inhibitor
+==Reference==
+<ref group="xtra">PMID:023362938</ref><references group="xtra"/><references/>
+[[Category: Escherichia coli k-12]]
+[[Category: Threonine--tRNA ligase]]
+[[Category: Hilgers, M T.]]
+[[Category: Aminoacyl-trna synthetase]]
+[[Category: Antibacterial]]
+[[Category: Ligase-ligase inhibitor complex]]
+[[Category: Protein-inhibitor complex]]