2f9b: Difference between revisions

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OCA

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-[[Image:2f9b.gif|left|200px]]<br /><applet load="2f9b" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:2f9b.gif|left|200px]]
-caption="2f9b, resolution 2.54&Aring;" />
-'''Discovery of Novel Heterocyclic Factor VIIa Inhibitors'''<br />
+ {{Structure
+|PDB= 2f9b |SIZE=350|CAPTION= <scene name='initialview01'>2f9b</scene>, resolution 2.54&Aring;
+|SITE=
+|LIGAND= <scene name='pdbligand=N1H:{5-(5-AMINO-1H-PYRROLO[3,2-B]PYRIDIN-2-YL)-6-HYDROXY-3'-NITRO-BIPHENYL-3-YL]-ACETIC ACID'>N1H</scene>
+|ACTIVITY= [http://en.wikipedia.org/wiki/Coagulation_factor_VIIa Coagulation factor VIIa], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.21 3.4.21.21]
+|GENE= F7 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]), F3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
+}}
+'''Discovery of Novel Heterocyclic Factor VIIa Inhibitors'''
 ==Overview==
@@ Line 10: / Line 19: @@
 ==About this Structure==
-F9B is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=N1H:'>N1H</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Coagulation_factor_VIIa Coagulation factor VIIa], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.21 3.4.21.21] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F9B OCA].
+F9B is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F9B OCA].
 ==Reference==
-Discovery of novel heterocyclic factor VIIa inhibitors., Rai R, Kolesnikov A, Sprengeler PA, Torkelson S, Ton T, Katz BA, Yu C, Hendrix J, Shrader WD, Stephens R, Cabuslay R, Sanford E, Young WB, Bioorg Med Chem Lett. 2006 Apr 15;16(8):2270-3. Epub 2006 Feb 3. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16460932 16460932]
+Discovery of novel heterocyclic factor VIIa inhibitors., Rai R, Kolesnikov A, Sprengeler PA, Torkelson S, Ton T, Katz BA, Yu C, Hendrix J, Shrader WD, Stephens R, Cabuslay R, Sanford E, Young WB, Bioorg Med Chem Lett. 2006 Apr 15;16(8):2270-3. Epub 2006 Feb 3. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16460932 16460932]
 [[Category: Coagulation factor VIIa]]
 [[Category: Homo sapiens]]
@@ Line 35: / Line 44: @@
 [[Category: short hydrogen bond]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:19:02 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:49:40 2008''