4k4z: Difference between revisions
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{{STRUCTURE_4k4z| PDB=4k4z | SCENE= }} | |||
===Coxsackievirus B3 polymerase elongation complex (r2_Mg_form)=== | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/Q66338_9ENTO Q66338_9ENTO]] Protein 2C associates with and induces structural rearrangements of intracellular membranes. It displays RNA-binding, nucleotide binding and NTPase activities (By similarity).[SAAS:SAAS001676_004_016611] Protein 3C is a cysteine protease that generates mature viral proteins from the precursor polyprotein. In addition to its proteolytic activity, it binds to viral RNA, and thus influences viral genome replication. RNA and substrate bind co-operatively to the protease (By similarity).[SAAS:SAAS000199_004_042266] RNA-directed RNA polymerase 3D-POL replicates genomic and antigenomic RNA by recognizing replications specific signals (By similarity).[SAAS:SAAS001676_004_010047] | |||
==About this Structure== | |||
[[4k4z]] is a 16 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_coxsackievirus_b3 Human coxsackievirus b3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K4Z OCA]. | |||
[[Category: Human coxsackievirus b3]] | |||
[[Category: Gong, P.]] | |||
[[Category: Peersen, O B.]] | |||
[[Category: Polymerase]] | |||
[[Category: Protein-rna complex]] | |||
[[Category: Rna-dependent rna polymerase]] | |||
[[Category: Transferase-rna complex]] | |||
Revision as of 09:27, 20 June 2013
Coxsackievirus B3 polymerase elongation complex (r2_Mg_form)Coxsackievirus B3 polymerase elongation complex (r2_Mg_form)
FunctionFunction
[Q66338_9ENTO] Protein 2C associates with and induces structural rearrangements of intracellular membranes. It displays RNA-binding, nucleotide binding and NTPase activities (By similarity).[SAAS:SAAS001676_004_016611] Protein 3C is a cysteine protease that generates mature viral proteins from the precursor polyprotein. In addition to its proteolytic activity, it binds to viral RNA, and thus influences viral genome replication. RNA and substrate bind co-operatively to the protease (By similarity).[SAAS:SAAS000199_004_042266] RNA-directed RNA polymerase 3D-POL replicates genomic and antigenomic RNA by recognizing replications specific signals (By similarity).[SAAS:SAAS001676_004_010047]
About this StructureAbout this Structure
4k4z is a 16 chain structure with sequence from Human coxsackievirus b3. Full crystallographic information is available from OCA.