3n2l: Difference between revisions

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-{{STRUCTURE_3n2l|  PDB=3n2l  |  SCENE=  }}
+==2.1 Angstrom resolution crystal structure of an Orotate Phosphoribosyltransferase (pyrE) from Vibrio cholerae O1 biovar eltor str. N16961==
-===2.1 Angstrom resolution crystal structure of an Orotate Phosphoribosyltransferase (pyrE) from Vibrio cholerae O1 biovar eltor str. N16961===
+<StructureSection load='3n2l' size='340' side='right' caption='[[3n2l]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
+== Structural highlights ==
-==Function==
+<table><tr><td colspan='2'>[[3n2l]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Vibrio_cholerae Vibrio cholerae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N2L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3N2L FirstGlance]. <br>
-[[http://www.uniprot.org/uniprot/PYRE_VIBCH PYRE_VIBCH]] Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity).
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
+<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pyrE, VC_0211 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=666 Vibrio cholerae])</td></tr>
-==About this Structure==
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Orotate_phosphoribosyltransferase Orotate phosphoribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.10 2.4.2.10] </span></td></tr>
-[[3n2l]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Vibrio_cholerae Vibrio cholerae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N2L OCA].
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3n2l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3n2l OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3n2l RCSB], [http://www.ebi.ac.uk/pdbsum/3n2l PDBsum]</span></td></tr>
+</table>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/n2/3n2l_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
+<div style="clear:both"></div>
 ==See Also==
 *[[Phosphoribosyltransferase|Phosphoribosyltransferase]]
+__TOC__
+</StructureSection>
 [[Category: Orotate phosphoribosyltransferase]]
 [[Category: Vibrio cholerae]]
-[[Category: Anderson, W F.]]
+[[Category: Anderson, W F]]
-[[Category: CSGID, Center for Structural Genomics of Infectious Diseases.]]
+[[Category: Structural genomic]]
-[[Category: Dubrovska, I.]]
+[[Category: Dubrovska, I]]
-[[Category: Halavaty, A S.]]
+[[Category: Halavaty, A S]]
-[[Category: Kwon, K.]]
+[[Category: Kwon, K]]
-[[Category: Minasov, G.]]
+[[Category: Minasov, G]]
-[[Category: Shuvalova, L.]]
+[[Category: Shuvalova, L]]
-[[Category: Winsor, J.]]
+[[Category: Winsor, J]]
-[[Category: Center for structural genomics of infectious disease]]
 [[Category: Csgid]]
 [[Category: Glycosyltransferase]]
 [[Category: Infectious disease]]
 [[Category: Magnesium]]
-[[Category: Orotate phosphoribosyltransferase]]
 [[Category: Pyrimidine biosynthesis]]
 [[Category: Pyrimidine ribonucleotide biosynthesis]]
 [[Category: Transferase]]