3n8h: Difference between revisions

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{{STRUCTURE_3n8h|  PDB=3n8h  |  SCENE=  }}
==Crystal Structure of Pantoate-beta-alanine Ligase from Francisella tularensis==
===Crystal Structure of Pantoate-beta-alanine Ligase from Francisella tularensis===
<StructureSection load='3n8h' size='340' side='right' caption='[[3n8h]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
 
== Structural highlights ==
==Function==
<table><tr><td colspan='2'>[[3n8h]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Francisella_tularensis_subsp._tularensis Francisella tularensis subsp. tularensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N8H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3N8H FirstGlance]. <br>
[[http://www.uniprot.org/uniprot/PANC_FRATT PANC_FRATT]] Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity).  
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PRO:PROLINE'>PRO</scene></td></tr>
 
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
==About this Structure==
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">FTT_1390, panC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=119856 Francisella tularensis subsp. tularensis])</td></tr>
[[3n8h]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Francisella_tularensis_subsp._tularensis Francisella tularensis subsp. tularensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N8H OCA].  
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pantoate--beta-alanine_ligase Pantoate--beta-alanine ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.2.1 6.3.2.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3n8h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3n8h OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3n8h RCSB], [http://www.ebi.ac.uk/pdbsum/3n8h PDBsum]</span></td></tr>
</table>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/n8/3n8h_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Pantothenate synthetase|Pantothenate synthetase]]
*[[Pantothenate synthetase|Pantothenate synthetase]]
__TOC__
</StructureSection>
[[Category: Francisella tularensis subsp. tularensis]]
[[Category: Francisella tularensis subsp. tularensis]]
[[Category: Pantoate--beta-alanine ligase]]
[[Category: Pantoate--beta-alanine ligase]]
[[Category: Anderson, W F.]]
[[Category: Anderson, W F]]
[[Category: Joachimiak, A.]]
[[Category: Joachimiak, A]]
[[Category: Kim, Y.]]
[[Category: Kim, Y]]
[[Category: Maltseva, N.]]
[[Category: Maltseva, N]]
[[Category: Papazisi, L.]]
[[Category: Papazisi, L]]
[[Category: Alpha-beta sandwich]]
[[Category: Alpha-beta sandwich]]
[[Category: Center for structural genomics of infectious disease]]
[[Category: Structural genomic]]
[[Category: Csgid]]
[[Category: Csgid]]
[[Category: Ligase]]
[[Category: Ligase]]
[[Category: Structural genomic]]
[[Category: Structural genomics of infectious disease]]

Revision as of 18:15, 18 December 2014

Crystal Structure of Pantoate-beta-alanine Ligase from Francisella tularensisCrystal Structure of Pantoate-beta-alanine Ligase from Francisella tularensis

Structural highlights

3n8h is a 2 chain structure with sequence from Francisella tularensis subsp. tularensis. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, , ,
NonStd Res:
Gene:FTT_1390, panC (Francisella tularensis subsp. tularensis)
Activity:Pantoate--beta-alanine ligase, with EC number 6.3.2.1
Resources:FirstGlance, OCA, RCSB, PDBsum

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

3n8h, resolution 2.00Å

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