4bea: Difference between revisions

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

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-'''Unreleased structure'''
+{{STRUCTURE_4bea|  PDB=4bea  |  SCENE=  }}
+===Crystal Structure of eIF4E in Complex with a Stapled Peptide Derivative===
-The entry 4bea is ON HOLD  until Paper Publication
+==Function==
+[[http://www.uniprot.org/uniprot/IF4E_HUMAN IF4E_HUMAN]] Its translation stimulation activity is repressed by binding to the complex CYFIP1-FMR1 (By similarity). Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates the binding to the mRNA cap.<ref>PMID:16271312</ref>
-Authors: Quah, S.T., Lama, D., Verma, C.S., Lane, D.P., Brown, C.J.
+==About this Structure==
+[[4bea]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BEA OCA].
-Description: Crystal Structure of eIF4E in Complex with a Stapled Peptide Derivative
+==Reference==
+<references group="xtra"/><references/>
+[[Category: Brown, C J.]]
+[[Category: Lama, D.]]
+[[Category: Lane, D P.]]
+[[Category: Quah, S T.]]
+[[Category: Verma, C S.]]
+[[Category: Translation]]