3m3h: Difference between revisions

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{{STRUCTURE_3m3h|  PDB=3m3h  |  SCENE=  }}
==1.75 Angstrom resolution crystal structure of an orotate phosphoribosyltransferase from Bacillus anthracis str. 'Ames Ancestor'==
===1.75 Angstrom resolution crystal structure of an orotate phosphoribosyltransferase from Bacillus anthracis str. 'Ames Ancestor'===
<StructureSection load='3m3h' size='340' side='right' caption='[[3m3h]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
 
== Structural highlights ==
==Function==
<table><tr><td colspan='2'>[[3m3h]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M3H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3M3H FirstGlance]. <br>
[[http://www.uniprot.org/uniprot/PYRE_BACAN PYRE_BACAN]] Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity).  
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
 
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pyrE, BA_4021, GBAA_4021, BAS3733 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1392 Bacillus anthracis])</td></tr>
==About this Structure==
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Orotate_phosphoribosyltransferase Orotate phosphoribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.10 2.4.2.10] </span></td></tr>
[[3m3h]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M3H OCA].  
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3m3h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3m3h OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3m3h RCSB], [http://www.ebi.ac.uk/pdbsum/3m3h PDBsum]</span></td></tr>
</table>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/m3/3m3h_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Phosphoribosyltransferase|Phosphoribosyltransferase]]
*[[Phosphoribosyltransferase|Phosphoribosyltransferase]]
__TOC__
</StructureSection>
[[Category: Bacillus anthracis]]
[[Category: Bacillus anthracis]]
[[Category: Orotate phosphoribosyltransferase]]
[[Category: Orotate phosphoribosyltransferase]]
[[Category: Anderson, W F.]]
[[Category: Anderson, W F]]
[[Category: CSGID, Center for Structural Genomics of Infectious Diseases.]]
[[Category: Structural genomic]]
[[Category: Dubrovska, I.]]
[[Category: Dubrovska, I]]
[[Category: Halavaty, A S.]]
[[Category: Halavaty, A S]]
[[Category: Kwon, K.]]
[[Category: Kwon, K]]
[[Category: Minasov, G.]]
[[Category: Minasov, G]]
[[Category: Shuvalova, L.]]
[[Category: Shuvalova, L]]
[[Category: Winsor, J.]]
[[Category: Winsor, J]]
[[Category: Center for structural genomics of infectious disease]]
[[Category: Csgid]]
[[Category: Csgid]]
[[Category: Glycosyltransferase]]
[[Category: Glycosyltransferase]]
[[Category: Infectious disease]]
[[Category: Infectious disease]]
[[Category: Magnesium]]
[[Category: Magnesium]]
[[Category: Orotate phosphoribosyltransferase]]
[[Category: Pyrimidine biosynthesis]]
[[Category: Pyrimidine biosynthesis]]
[[Category: Pyrimidine ribonucleotide biosynthesis]]
[[Category: Pyrimidine ribonucleotide biosynthesis]]
[[Category: Structural genomic]]
[[Category: Transferase]]
[[Category: Transferase]]

Revision as of 18:18, 18 December 2014

1.75 Angstrom resolution crystal structure of an orotate phosphoribosyltransferase from Bacillus anthracis str. 'Ames Ancestor'1.75 Angstrom resolution crystal structure of an orotate phosphoribosyltransferase from Bacillus anthracis str. 'Ames Ancestor'

Structural highlights

3m3h is a 1 chain structure with sequence from Bacillus anthracis. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
Gene:pyrE, BA_4021, GBAA_4021, BAS3733 (Bacillus anthracis)
Activity:Orotate phosphoribosyltransferase, with EC number 2.4.2.10
Resources:FirstGlance, OCA, RCSB, PDBsum

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

3m3h, resolution 1.75Å

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