2e9a: Difference between revisions

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[[Image:2e9a.jpg|left|200px]]<br /><applet load="2e9a" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2e9a.jpg|left|200px]]
caption="2e9a, resolution 2.1&Aring;" />
 
'''E. coli undecaprenyl pyrophosphate synthase in complex with BPH-628'''<br />
{{Structure
|PDB= 2e9a |SIZE=350|CAPTION= <scene name='initialview01'>2e9a</scene>, resolution 2.1&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=B28:(1-HYDROXY-1-PHOSPHONO-2-[1,1';4',1'']TERPHENYL-3-YL-ETHYL)-PHOSPHONIC ACID'>B28</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Di-trans,poly-cis-decaprenylcistransferase Di-trans,poly-cis-decaprenylcistransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.31 2.5.1.31]
|GENE=
}}
 
'''E. coli undecaprenyl pyrophosphate synthase in complex with BPH-628'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2E9A is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=B28:'>B28</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Di-trans,poly-cis-decaprenylcistransferase Di-trans,poly-cis-decaprenylcistransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.31 2.5.1.31] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E9A OCA].  
2E9A is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E9A OCA].  


==Reference==
==Reference==
Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases., Guo RT, Cao R, Liang PH, Ko TP, Chang TH, Hudock MP, Jeng WY, Chen CK, Zhang Y, Song Y, Kuo CJ, Yin F, Oldfield E, Wang AH, Proc Natl Acad Sci U S A. 2007 Jun 12;104(24):10022-7. Epub 2007 May 29. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17535895 17535895]
Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases., Guo RT, Cao R, Liang PH, Ko TP, Chang TH, Hudock MP, Jeng WY, Chen CK, Zhang Y, Song Y, Kuo CJ, Yin F, Oldfield E, Wang AH, Proc Natl Acad Sci U S A. 2007 Jun 12;104(24):10022-7. Epub 2007 May 29. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17535895 17535895]
[[Category: Di-trans,poly-cis-decaprenylcistransferase]]
[[Category: Di-trans,poly-cis-decaprenylcistransferase]]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: prenyltransferase]]
[[Category: prenyltransferase]]


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