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{{STRUCTURE_4iv3| PDB=4iv3 | SCENE= }} | |||
===Crystal structure of recombinant foot-and-mouth-disease virus A22-H2093C empty capsid=== | |||
{{ABSTRACT_PUBMED_23544011}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/Q6PN23_9PICO Q6PN23_9PICO]] Protein 3C is a cysteine protease that generates mature viral proteins from the precursor polyprotein. In addition to its proteolytic activity, it binds to viral RNA, and thus influences viral genome replication. RNA and substrate bind co-operatively to the protease (By similarity).[SAAS:SAAS000199_004_042266] RNA-directed RNA polymerase 3D-POL replicates genomic and antigenomic RNA by recognizing replications specific signals (By similarity).[SAAS:SAAS000199_004_010047] | |||
==About this Structure== | |||
[[4iv3]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Foot-and-mouth_disease_virus_-_type_a Foot-and-mouth disease virus - type a]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IV3 OCA]. | |||
[[Category: Foot-and-mouth disease virus - type a]] | |||
[[Category: Burman, A.]] | |||
[[Category: Charleston, B.]] | |||
[[Category: Fry, E E.]] | |||
[[Category: Jackson, T.]] | |||
[[Category: Jones, I M.]] | |||
[[Category: Kotecha, A.]] | |||
[[Category: Loureiro, S.]] | |||
[[Category: Porta, C.]] | |||
[[Category: Ren, J.]] | |||
[[Category: Stuart, D I.]] | |||
[[Category: Apthovirus]] | |||
[[Category: Capsid]] | |||
[[Category: Icosahedral virus]] | |||
[[Category: Picornavirus]] | |||
[[Category: Vaccine]] | |||
[[Category: Virus]] |
Revision as of 23:27, 17 April 2013
Crystal structure of recombinant foot-and-mouth-disease virus A22-H2093C empty capsidCrystal structure of recombinant foot-and-mouth-disease virus A22-H2093C empty capsid
Template:ABSTRACT PUBMED 23544011
FunctionFunction
[Q6PN23_9PICO] Protein 3C is a cysteine protease that generates mature viral proteins from the precursor polyprotein. In addition to its proteolytic activity, it binds to viral RNA, and thus influences viral genome replication. RNA and substrate bind co-operatively to the protease (By similarity).[SAAS:SAAS000199_004_042266] RNA-directed RNA polymerase 3D-POL replicates genomic and antigenomic RNA by recognizing replications specific signals (By similarity).[SAAS:SAAS000199_004_010047]
About this StructureAbout this Structure
4iv3 is a 4 chain structure with sequence from Foot-and-mouth disease virus - type a. Full crystallographic information is available from OCA.