4ber: Difference between revisions

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-'''Unreleased structure'''
+{{STRUCTURE_4ber|  PDB=4ber  |  SCENE=  }}
+===Crystal structure of the Legionella pneumophila FIC domain-containing effector AnkX protein in complex with cytidine monophosphate===
+{{ABSTRACT_PUBMED_23572077}}
-The entry 4ber is ON HOLD  until Paper Publication
+==Function==
+[[http://www.uniprot.org/uniprot/ANKX_LEGPH ANKX_LEGPH]] Virulence effector that plays a role in hijacking the host vesicular trafficking by recruiting the small guanosine triphosphatase (GTPase) Rab1 to the cytosolic face of the Legionella-containing vacuole (LCVs). Acts as a phosphocholine transferase by mediating the addition of phosphocholine to Ser residues of host RAB1 (RAB1A, RAB1B or RAB1C) and RAB35, leading to displacement of GDP dissociation inhibitors (GDI). Phosphocholination of target proteins also impairs accessibility to GTPase effector LepB. Can act on both GDP-bound and GTP-bound Rab proteins.<ref>PMID:18566289</ref> <ref>PMID:22158903</ref> <ref>PMID:21822290</ref> <ref>PMID:22307087</ref> <ref>PMID:22411835</ref>
-Authors: Campanacci, V., Mukherjee, S., Roy, C.R., Cherfils, J.
+==About this Structure==
+[[4ber]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Legionella_pneumophila Legionella pneumophila]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BER OCA].
-Description: Crystal structure of the Legionella pneumophila FIC domain-containing effector AnkX protein in complex with cytidine monophosphate
+==Reference==
+<references group="xtra"/><references/>
+[[Category: Legionella pneumophila]]
+[[Category: Campanacci, V.]]
+[[Category: Cherfils, J.]]
+[[Category: Mukherjee, S.]]
+[[Category: Roy, C R.]]
+[[Category: Transferase]]
+[[Category: Type iv secretion system effector]]