2dg3: Difference between revisions

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[[Image:2dg3.gif|left|200px]]<br /><applet load="2dg3" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2dg3.gif|left|200px]]
caption="2dg3, resolution 1.70&Aring;" />
 
'''Wildtype FK506-binding protein complexed with Rapamycin'''<br />
{{Structure
|PDB= 2dg3 |SIZE=350|CAPTION= <scene name='initialview01'>2dg3</scene>, resolution 1.70&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=RAP:RAPAMYCIN+IMMUNOSUPPRESSANT+DRUG'>RAP</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Peptidylprolyl_isomerase Peptidylprolyl isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.2.1.8 5.2.1.8]
|GENE=
}}
 
'''Wildtype FK506-binding protein complexed with Rapamycin'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2DG3 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=RAP:'>RAP</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Peptidylprolyl_isomerase Peptidylprolyl isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.2.1.8 5.2.1.8] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DG3 OCA].  
2DG3 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DG3 OCA].  


==Reference==
==Reference==
Energetic and structural analysis of the role of tryptophan 59 in FKBP12., Fulton KF, Jackson SE, Buckle AM, Biochemistry. 2003 Mar 4;42(8):2364-72. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12600203 12600203]
Energetic and structural analysis of the role of tryptophan 59 in FKBP12., Fulton KF, Jackson SE, Buckle AM, Biochemistry. 2003 Mar 4;42(8):2364-72. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12600203 12600203]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Peptidylprolyl isomerase]]
[[Category: Peptidylprolyl isomerase]]
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[[Category: rotamase]]
[[Category: rotamase]]


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