2c8y: Difference between revisions

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-[[Image:2c8y.gif|left|200px]]<br /><applet load="2c8y" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:2c8y.gif|left|200px]]
-caption="2c8y, resolution 2.20&Aring;" />
-'''THROMBIN INHIBITORS'''<br />
+ {{Structure
+|PDB= 2c8y |SIZE=350|CAPTION= <scene name='initialview01'>2c8y</scene>, resolution 2.20&Aring;
+|SITE= <scene name='pdbsite=AC1:C3m+Binding+Site+For+Chain+B'>AC1</scene>
+|LIGAND= <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene> and <scene name='pdbligand=C3M:N-[(2R,3S)-3-AMINO-2-HYDROXY-4-PHENYLBUTYL]NAPHTHALENE-2-SULFONAMIDE'>C3M</scene>
+|ACTIVITY= [http://en.wikipedia.org/wiki/Thrombin Thrombin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.5 3.4.21.5]
+|GENE=
+}}
+'''THROMBIN INHIBITORS'''
 ==Overview==
@@ Line 10: / Line 19: @@
 ==About this Structure==
-C8Y is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Hirudo_medicinalis Hirudo medicinalis] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=NA:'>NA</scene>, <scene name='pdbligand=DMS:'>DMS</scene> and <scene name='pdbligand=C3M:'>C3M</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Thrombin Thrombin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.5 3.4.21.5] Known structural/functional Site: <scene name='pdbsite=AC1:C3m+Binding+Site+For+Chain+B'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C8Y OCA].
+C8Y is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Hirudo_medicinalis Hirudo medicinalis] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C8Y OCA].
 ==Reference==
-Application of fragment screening and fragment linking to the discovery of novel thrombin inhibitors., Howard N, Abell C, Blakemore W, Chessari G, Congreve M, Howard S, Jhoti H, Murray CW, Seavers LC, van Montfort RL, J Med Chem. 2006 Feb 23;49(4):1346-55. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16480269 16480269]
+Application of fragment screening and fragment linking to the discovery of novel thrombin inhibitors., Howard N, Abell C, Blakemore W, Chessari G, Congreve M, Howard S, Jhoti H, Murray CW, Seavers LC, van Montfort RL, J Med Chem. 2006 Feb 23;49(4):1346-55. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16480269 16480269]
 [[Category: Hirudo medicinalis]]
 [[Category: Homo sapiens]]
@@ Line 47: / Line 56: @@
 [[Category: zymogen]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:46:14 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:12:24 2008''