2c0q: Difference between revisions

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[[Image:2c0q.gif|left|200px]]<br /><applet load="2c0q" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2c0q.gif|left|200px]]
caption="2c0q, resolution 2.50&Aring;" />
 
'''NON-AGED FORM OF MOUSE ACETYLCHOLINESTERASE INHIBITED BY TABUN'''<br />
{{Structure
|PDB= 2c0q |SIZE=350|CAPTION= <scene name='initialview01'>2c0q</scene>, resolution 2.50&Aring;
|SITE= <scene name='pdbsite=AC1:P6g+Binding+Site+For+Chain+B'>AC1</scene>
|LIGAND= <scene name='pdbligand=NTJ:R-ETHYL+N,N-DIMETHYLPHOSPHONAMIDATE'>NTJ</scene> and <scene name='pdbligand=P6G:HEXAETHYLENE GLYCOL'>P6G</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Acetylcholinesterase Acetylcholinesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.7 3.1.1.7]
|GENE=
}}
 
'''NON-AGED FORM OF MOUSE ACETYLCHOLINESTERASE INHIBITED BY TABUN'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2C0Q is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] with <scene name='pdbligand=NTJ:'>NTJ</scene> and <scene name='pdbligand=P6G:'>P6G</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Acetylcholinesterase Acetylcholinesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.7 3.1.1.7] Known structural/functional Site: <scene name='pdbsite=AC1:P6g+Binding+Site+For+Chain+B'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C0Q OCA].  
2C0Q is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C0Q OCA].  


==Reference==
==Reference==
Structural changes of phenylalanine 338 and histidine 447 revealed by the crystal structures of tabun-inhibited murine acetylcholinesterase., Ekstrom F, Akfur C, Tunemalm AK, Lundberg S, Biochemistry. 2006 Jan 10;45(1):74-81. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16388582 16388582]
Structural changes of phenylalanine 338 and histidine 447 revealed by the crystal structures of tabun-inhibited murine acetylcholinesterase., Ekstrom F, Akfur C, Tunemalm AK, Lundberg S, Biochemistry. 2006 Jan 10;45(1):74-81. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16388582 16388582]
[[Category: Acetylcholinesterase]]
[[Category: Acetylcholinesterase]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: serine esterase]]
[[Category: serine esterase]]


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