4jeu: Difference between revisions
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{{STRUCTURE_4jeu| PDB=4jeu | SCENE= }} | |||
===Crystal Structure of Munc18a and Syntaxin1 with native N-terminus complex=== | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/STXB1_RAT STXB1_RAT]] May participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. Essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. Can interact with syntaxins 1, 2, and 3 but not syntaxin 4. May play a role in determining the specificity of intracellular fusion reactions. [[http://www.uniprot.org/uniprot/STX1A_RAT STX1A_RAT]] Potentially involved in docking of synaptic vesicles at presynaptic active zones. May play a critical role in neurotransmitter exocytosis. May mediate Ca(2+)-regulation of exocytosis acrosomal reaction in sperm. | |||
==About this Structure== | |||
[[4jeu]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JEU OCA]. | |||
[[Category: Rattus norvegicus]] | |||
[[Category: Burkhardt, P.]] | |||
[[Category: Colbert, K N.]] | |||
[[Category: Fasshauer, D.]] | |||
[[Category: Hattendorf, D A.]] | |||
[[Category: Weis, W I.]] | |||
[[Category: Weiss, T M.]] | |||
[[Category: Endocytosis-exocytosis complex]] | |||
[[Category: Membrane]] | |||
[[Category: Neurotransmitter transport]] | |||
[[Category: Phosphoprotein]] | |||
[[Category: Protein complex]] | |||
[[Category: Protein transport]] | |||
[[Category: Transmembrane]] | |||
[[Category: Transport]] | |||