2brk: Difference between revisions

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[[Image:2brk.gif|left|200px]]<br /><applet load="2brk" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2brk.gif|left|200px]]
caption="2brk, resolution 2.30&Aring;" />
 
'''CRYSTAL STRUCTURE OF HEPATITIS C VIRUS POLYMERASE IN COMPLEX WITH AN ALLOSTERIC INHIBITOR (COMPOUND 1)'''<br />
{{Structure
|PDB= 2brk |SIZE=350|CAPTION= <scene name='initialview01'>2brk</scene>, resolution 2.30&Aring;
|SITE= <scene name='pdbsite=AC1:Cmf+Binding+Site+For+Chain+A'>AC1</scene>
|LIGAND= <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene> and <scene name='pdbligand=CMF:3-CYCLOHEXYL-1-(2-MORPHOLIN-4-YL-2-OXOETHYL)-2-PHENYL-1H-INDOLE-6-CARBOXYLIC ACID'>CMF</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/RNA-directed_RNA_polymerase RNA-directed RNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.48 2.7.7.48]
|GENE=
}}
 
'''CRYSTAL STRUCTURE OF HEPATITIS C VIRUS POLYMERASE IN COMPLEX WITH AN ALLOSTERIC INHIBITOR (COMPOUND 1)'''
 


==About this Structure==
==About this Structure==
2BRK is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Gb_virus_c Gb virus c] with <scene name='pdbligand=MN:'>MN</scene> and <scene name='pdbligand=CMF:'>CMF</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/RNA-directed_RNA_polymerase RNA-directed RNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.48 2.7.7.48] Known structural/functional Site: <scene name='pdbsite=AC1:Cmf+Binding+Site+For+Chain+A'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BRK OCA].  
2BRK is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Gb_virus_c Gb virus c]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BRK OCA].  
[[Category: Gb virus c]]
[[Category: Gb virus c]]
[[Category: RNA-directed RNA polymerase]]
[[Category: RNA-directed RNA polymerase]]
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[[Category: transferase]]
[[Category: transferase]]


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